METABOLIC CORRELATES OF PEDUNCULOPONTINE NUCLEUS DEEP BRAIN STIMULATION IN PD

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这项研究将利用先进的成像方法来阐明桥小脑脚核脑深部刺激对帕金森病患者临床效果的神经生理学机制。除了提供有关正常脑功能以及帕金森氏症患者大脑功能如何改变的有价值的信息外，这项拟议的研究还将为临床实践中选择这一程序的患者提供实用有用的信息。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study will utilize advanced imaging methods to elucidate the neurophysiological mechanisms underlying the clinical effects of pedunculopontine nucleus deep brain stimulation in patients with Parkinson's disease. In addition to providing valuable information regarding normal brain function and how this is altered in Parkinson's disease, the proposed study will provide practically useful information regarding patient selection for this procedure in clinical practice.