OBESITY INTERVENTION BIOMARKER FOLLOW-UP STUDY IN RURAL PENNSYLVANIA FAMILIES

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 肥胖症的流行要求发展合作的社区研究伙伴关系，这种伙伴关系是创新的，可以促进变革，从而改善公共卫生。与北阿巴拉契亚癌症网络(NACN)和宾夕法尼亚州州立癌症研究所(PSCI)合作，我们正在为宾夕法尼亚州农村低收入家庭开发干预措施。这项干预研究目前由宾夕法尼亚州立大学外联健康专题倡议基金资助，作为一个试点项目，以评估干预后食物选择的变化，并在基线上采集血样。 我们的目标是对作为晚餐俱乐部的干预措施的工具、程序和内容进行试点测试，以通过培训和为食物准备者提供信息和食物配菜来促进家庭内部的健康。我们还将收集生物标本，以确定教育干预后血清瘦素是上升还是下降。 主题：将包括20个家庭，每个家庭一个儿童/一个成人。参赛者将年龄在7岁至60岁之间，父母一人，自报身高，体重计算BMI在成人超重范围内(BMI=25)，两人均能提供血样，成人血样为50毫升/公斤，儿童血样不超过3毫升/公斤，成年月经女性参与者在月经周期前后同时提供血样。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The epidemic of obesity calls for the development of collaborative community-research partnerships that are innovative and that can foster change that results in improved public health. In collaboration with the Northern Appalachia Cancer Network (NACN) and the Penn State Cancer Institute (PSCI), we are developing an intervention for low-income families of rural Pennsylvania. This intervention study is currently funded by the Penn State Outreach Health Thematic Initiative Fund as a pilot project to assess changes in food choices post intervention and to collect blood samples at baseline. Our objective is to pilot test the instruments, procedures, and content of an intervention designed as a supper club to promote wellness within the family through training and providing the food preparer with information and food side dishes to serve at family meals. We will also collect biologic specimens to determine whether serum leptin increases or decreases following the educational intervention. Subjects: will include 20 families, one child/one adult per family. Participate will be 7 to 60 years of age, child and one parent, self reported height, weight calculated BMI in the overweight range for the adult (BMI =25), both able to give a blood sample of 50 mls for adults and no more than 3 ml per kg for child, adult menstruating women participants to provide blood sample at the same time in the menstrual cycle during pre- and post-measurement.