SUBMICRON SENSOR POSITIONING WITH REPEATABILITY AND STABILITY

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 计算机控制的亚微米定位将使我们能够研究非接触式细胞膜检测方法，用作位置调节器。为此，我们打算探索使用压电管定位器除了我们的线性步进电机的方法。 为了在3个轴上驱动压电管，需要5个双极电压源。PIC 16 f73的脉宽调制器用于构建一对能够产生高达500伏的升压转换器。PIC通过片上模数转换器监控电压，并调整其脉宽监控器上的占空比，以达到主机要求的电压。对于超精细控制，可以使用模拟输入来设置通过一对晶体管的电压。在此模式下，PIC将升压转换器的电位设置为高于请求值2伏，以减少发热。一个很好的位置属性已被添加到允许定位器与现有的BRC微操作器顺利工作。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Computer controlled submicron positioning will enable us to investigate methods of non-contact cell membrane detection for use as a position regulator. To this end we intend to explore the use of piezo tube positioners in addition to our linear stepper motor approach. To drive a piezo tube in 3 axes, 5 bipolar voltage sources are needed. The pulse width modulators from a PIC16f73 are used to construct a pair of boost converters capable of producing up to ¿500 Volts. The PIC monitors the voltage through an on-chip analog to digital converter and adjusts the duty cycle on its pulse width monitor to achieve the voltage requested by the host computer. For ultra fine control, analog inputs may be used to set the voltage through a pair of transistors. In this mode the PIC will set the boost converters potential 2 volts above the requested value to reduce heating. A fine position property has been added to allow the positioner to work smoothly with the existing BRC micro-manipulator.