129XE POLARIZATION OPTIMIZATION AND IMAGING METHOD DEVELOPMENT

该子项目是利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得主要资金， 因此可以在其他CRISP条目中表示。列出的机构是 中心，不一定是研究者的机构。 该项目的目标是 - 改善129 nm的偏振和音量，并展示更高的图像质量 - 开发新的成像和光谱范例，这将提供迄今为止无法获得的肺功能信息 改进图像的演示对于显示偏振增强的实用性至关重要。 方法将包括129 μ m线圈的开发，调整和测试与phantomy;健康动物通气成像与PR和GRASS序列;肺膜光谱序列的发展。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The goals of this project are to - Improve the polarization and volume of 129Xe and to demonstrate increased image quality - Develop novel imaging and spectroscopy paradigms, which will give heretofore unobtainable information about lung function Demonstration of improved images is critical to show the utility of the polarization enhancement. Methods will include 129Xe coil development, tuning and testing with phantoms; healthy animal ventilation imaging with PR and GRASS sequences; development of pulmonary membrane spectroscopy sequences.