METABOLIC CORRELATES OF FUNCTIONAL MRI

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目及 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本项目的总体目标是开发和验证一种同时测量 脑血流量（CBF）和葡萄糖代谢，使用MRI和PET的多模式成像。 受试者在功能性MRI（fMRI）期间输注19 F-氟脱氧葡萄糖（FDG）， 随后用PET扫描测量fMRI期间的葡萄糖利用。这项技术 在研究健康人群脑血流与代谢的耦合方面具有广泛的应用前景 和疾病

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The overall goal of this project is to develop and validate a method for concurrent measurement of cerebral blood flow (CBF) and glucose metabolism using multimodal imaging with MRI and PET. Subjects are infused with 19F-fluorodeoxyglucose (FDG) during functional MRI (fMRI), and glucose utilization during the fMRI is subsequently measured with PET scanning. This technology will have a variety of applications in studying the coupling between CBF and metabolism in health and disease.