CIRCLE OF WILLIS VARIABILITY AND MIGRAINE

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 该项目的中心假设是威利斯异常环圈与 脑血流动力学与偏头痛易感性和脑缺血并发症的关系 偏头痛。本项目使用ASL、渡越时间标测、高分辨率MRA和fMRI来研究 偏头痛患者Willis环结构变异及相关功能改变 与匹配的对照组相比。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The central hypothesis of this project is that circle of Willis anomalies correlate with alterations in cerebral hemodynamics and contribute to migraine susceptibility and ischemic complications of migraine. This project uses ASL, transit time mapping, high resolution MRA and fMRI to study the structural variation of Circle of Willis and associated functional changes in migraine patients compared to matched controls.