CIRCLE OF WILLIS VARIABILITY AND MIGRAINE

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 该项目的中心假设是威利斯异常环圈与 脑血流动力学与偏头痛易感性和脑缺血并发症的关系 偏头痛。本项目使用ASL、渡越时间标测、高分辨率MRA和fMRI来研究 偏头痛患者Willis环结构变异及相关功能改变 与匹配的对照组相比。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The central hypothesis of this project is that circle of Willis anomalies correlate with alterations in cerebral hemodynamics and contribute to migraine susceptibility and ischemic complications of migraine. This project uses ASL, transit time mapping, high resolution MRA and fMRI to study the structural variation of Circle of Willis and associated functional changes in migraine patients compared to matched controls.