CIRCLE OF WILLIS VARIABILITY AND MIGRAINE

威利斯变异与偏头痛的循环

• 批准号: 8169059
• 负责人: Brett Lee Cucchiara
• 金额: $ 1.73万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-01 至 2011-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8169059
• 关键词: Cerebrum; Circle of Willis; Computer Retrieval of Information on Scientific Projects Database; Functional Magnetic Resonance Imaging; Funding; Grant; Institution; Maps; Migraine; Patients; Predisposition; Research; Research Personnel; Resolution; Resources; Source; Time; United States National Institutes of Health; Variant; hemodynamics

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The central hypothesis of this project is that circle of Willis anomalies correlate with alterations in cerebral hemodynamics and contribute to migraine susceptibility and ischemic complications of migraine. This project uses ASL, transit time mapping, high resolution MRA and fMRI to study the structural variation of Circle of Willis and associated functional changes in migraine patients compared to matched controls.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 该项目的中心假设是Willis环异常与以下改变相关： 脑血流动力学和有助于偏头痛的易感性和缺血性并发症 偏头痛本项目使用ASL、渡越时间图、高分辨率MRA和fMRI来研究 偏头痛患者Willis环结构变异及相关功能改变 与对照组相比。