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CELL MODEL FOR KSHV INFECTION AND GENETIC MANIPULATION

CELL MODEL FOR KSHV INFECTION AND GENETIC MANIPULATION
KSHV 感染和基因操纵的细胞模型
批准号：
7957694
负责人：
Shou-Jiang Gao
金额：
$0.33万
依托单位：
UNIVERSITY OF WASHINGTON
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
项目状态：
已结题
起止时间：
2009-09-01 至 2010-08-31
来源：
https://reporter.nih.gov/project-details/7957694
关键词：
BiologyCell modelComputer Retrieval of Information on Scientific Projects DatabaseDNA Tumor VirusesFundingFungal GenomeGoalsGrantHuman Herpesvirus 8InfectionInstitutionKaposi SarcomaMalignant NeoplasmsMolecularPathogenesisPreventiveResearchResearch PersonnelResourcesSourceTherapeuticUnited States National Institutes of HealthVirusbasegenetic manipulation

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中文摘要
翻译
这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 Kaposi肉瘤(KS)相关疱疹病毒(KSHV/HHV8)是一种与KS和其他几种恶性肿瘤相关的DNA肿瘤病毒。申请人的长期目标是以KSHV为范例，了解病毒诱导致病的分子机制，为预防和治疗提供生物学基础。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Kaposi's sarcoma (KS)-associated herpesvirus (KSHV/HHV8) is a DNA tumor virus etiologically associated with KS and several other malignancies. The applicant's long-range goal is to use KSHV as a paradigm to understand the molecular mechanism of virus-induced pathogenesis, providing biologic basis for preventive and therapeutic purposes.
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会议论文
Citrulline-urea cycle in KSHV cellular transformation
Impact of microbiota on AIDS-Kaposi’s sarcoma development and therapy
Regulation of KSHV replication by N6-methyladenosine (m6A) - Diversity Supplement
HISTONE MODIFIERS IN ORAL KSHV INFECTION AND MALIGNANCIES
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