CHARACTERIZATION OF A NOVEL RACGAP SPLICE VARIANT

新型 RACGAP 拼接变体的特征

• 批准号: 7957713
• 负责人: GARY M BOKOCH
• 金额: $ 0.33万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2010-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7957713
• 关键词: Biology; Brain; Computer Retrieval of Information on Scientific Projects Database; Cytoskeletal Modeling; Funding; Fungal Genome; Grant; Human Cloning; Institution; Process; RNA Splicing; Research; Research Personnel; Resources; Role; Source; United States National Institutes of Health; Variant; novel

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This is a novel splice variant cloned from human brain. We have so far confirmed that this splice variant is expressed in brain, and are in the process of characterizing its cellular role in RhoGTPase activation and possible cytoskeletal reorganization. This is a new project that is not currently funded by a specific grant.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 这是从人脑中克隆的新型剪接变体。 到目前为止，我们已经证实这种剪接变体在大脑中表达，并且正在表征其在 RhoGTPase 激活和可能的细胞骨架重组中的细胞作用。 这是一个新项目，目前尚未获得特定补助金的资助。