COURSEWORK: UPR

课程：普遍定期审议

• 批准号: 7956104
• 负责人: RICARDO C GONZALEZ
• 金额: $ 0.08万
• 依托单位: CARNEGIE-MELLON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-01 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7956104
• 关键词: Algorithms; Amino Acid Sequence; Bioinformatics; Biological; Biomedical Research; CCL7 gene; Comprehension; Computational Biology; Computational Technique; Computer Retrieval of Information on Scientific Projects Database; Coupled; DNA; Data; Databases; Funding; Genome; Genomics; Grant; Hand; High Performance Computing; Imagery; Individual; Institution; Learning; Peptide Sequence Determination; Phylogenetic Analysis; Process; Research; Research Personnel; Resources; Sequence Analysis; Source; Students; Training; United States National Institutes of Health; biomedical scientist; computer program; computing resources; design; experience; flexibility; lectures; protein structure

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This grant is to provide access for a course in bioinformatics developed as part of the MARC Training Grant of Dr. Hugh Nicholas of the PSC. The course is designed to provide an understanding of important topics in applied bioinformatics and computational biology. Students will be able to learn about problems involved in the analysis of biological data such as DNA/protein sequences and protein structures. The course is intended to provide a good understanding of the commonly used algorithms in the analysis of genomic data, hands-on experiences with accessing and using relevant databases, the use of advanced computer programs for sequence analysis, protein sequence phylogenetic analysis, visualization of results, and a basic overview of genome analysis. The course is intended to be flexible and adaptable to students' needs. Its objectives are: to provide students with a thorough understanding of current computational techniques available to biomedical scientists for processing, analyzing, and understanding DNA and protein sequence and structural analysis. This will be accomplished through lectures, coupled with lab sessions where students will interact with the PSC Bioinformatics resources discussed in class. Student comprehension of computational biology concepts and utilization of the PSC computational resources will be assessed through individual projects which will evolve throughout the semester. In addition, students will be exposed to a variety of research avenues available to the computational biomedical scientist.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 这笔赠款旨在提供生物信息学课程的访问权限，该课程是 PSC 的 Hugh Nicholas 博士的 MARC 培训赠款的一部分。该课程旨在提供对应用生物信息学和计算生物学重要主题的理解。学生将能够了解 DNA/蛋白质序列和蛋白质结构等生物数据分析中涉及的问题。本课程旨在让学生更好地理解基因组数据分析中常用的算法、访问和使用相关数据库的实践经验、使用先进的计算机程序进行序列分析、蛋白质序列系统发育分析、结果可视化以及基因组分析的基本概述。该课程旨在灵活并适应学生的需求。其目标是：让学生全面了解生物医学科学家可用于处理、分析和理解 DNA 和蛋白质序列及结构分析的当前计算技术。这将通过讲座和实验室课程来完成，学生将在实验室课程中与课堂上讨论的 PSC 生物信息学资源进行互动。学生对计算生物学概念的理解和 PSC 计算资源的利用将通过整个学期发展的各个项目进行评估。此外，学生还将接触到计算生物医学科学家可用的各种研究途径。