SIMULATION OF ARTERIAL BLOOD FLOW DYNAMICS

动脉血流动力学模拟

• 批准号: 7956309
• 负责人: SHEWAFERAW SOLOMAN SHIBESHI
• 金额: $ 0.08万
• 依托单位: CARNEGIE-MELLON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-01 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7956309
• 关键词: Affect; Behavior; Biomedical Research; Blood flow; Cause of Death; Clinical; Clinical Research; Computer Retrieval of Information on Scientific Projects Database; Disease; Epidemiology; Equation; Fibrinogen; Funding; Grant; Hematocrit procedure; High Performance Computing; Institution; Liquid substance; Modeling; Research; Research Personnel; Resources; Role; Source; United States National Institutes of Health; blood rheology; simulation

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We would like to investigate the role of hematocrit in the genesis of arterial diseases using computational fluid dynamics approach. Current epidemiological and clinical studies show hematocrit level as one factor contributing to the genesis of arterial diseases. However, such findings lacks support of fundamental explanation. We use Navier Stock's equation and various blood rheology models to depict the flow dynamics and make analysis on how the flow behavior affects the onset of arterial diseases. Findings in this study provides theoretical explanation to earlier clinical and epidemiological findings to arterial diseases which are known to be one of the principal cause of death in the world.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 我们想利用计算流体动力学方法研究血细胞比容在动脉疾病起源中的作用。当前的流行病学和临床研究表明，血细胞比容水平是导致动脉疾病起源的一个因素。但是，这样的发现缺乏对基本解释的支持。我们使用Navier Stock的方程式和各种血液流变模型来描述流动动力学，并就流动行为如何影响动脉疾病的开始进行分析。这项研究的发现为较早的临床和流行病学发现对动脉疾病提供了理论解释，这些发现是世界上死亡的主要原因之一。