NEURAL CORRELATES OF AUDITOR FILL IN

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 一个基本的问题是：如何在复杂的声学环境中分离和分析发声对象？通过将行为与生理学相结合，精心构思行为问题，并利用基于信号检测理论的分析，我们将达到三个目的。 目的1：测量和比较猕猴和人类对牙体充填的感知。目标1将通过测量猕猴和人类检测前景声音的连续性的能力来实现，这是插入它们的间隙持续时间和干扰噪音强度的函数。 目标2：使用允许将听觉皮质神经元的反应与目标1的结果进行直接比较的分析来确定填充的神经相关性。 目的3：确定神经反应与多个皮质区域的行为表现和决策之间的关联强度。 为了实现目标2和3，将使用基于信号检测理论的分析--类似于上一段中提到的关于视觉系统的分析--。 实现这些目标将极大地促进对神经反应的理解，对听觉感知和决策的贡献。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. A fundamental question is: How can one segregate and analyze a sound-producing object in a complex acoustic environment? By combining behavior and physiology, carefully framing the behavioral question, and using signal detection theory based analyses we will achieve three aims. Aim 1: To measure and compare macaque and human perceptions of fill-in. Aim 1 will be achieved by measuring macaques' and humans' abilities to detect the continuity of foreground sounds as a function of the duration of gaps inserted into them and the intensity of an interrupting noise. Aim 2: To determine neural correlates of fill-in using analyses that allow for direct comparisons of auditory cortical neurons' responses to the results of Aim 1. Aim 3: To determine the strength of association between neural responses and behavioral performance and decisions in multiple cortical fields. To achieve Aims 2 nd 3, signal detection theory based analyses--similar to analyses referred to in the previous paragraph about the visual system--will be used. Achieving the aims will significantly advance the understanding of neural responses contributions to auditory perceptions and decision-making.