Inflammation and platelet activation
Inflammation and platelet activation
批准号:
7828104
负责人:
Craig Fletcher
金额:
$63.29万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
关键词:
AccountingAddressAdhesionsAffectAfrican AmericanAgeAgingAmputationArchivesArterial Fatty StreakArteriesAtherosclerosisBaltimoreBindingBiologicalBiological FactorsBiological MarkersBiological ProcessBlood PlateletsBlood VesselsBrainCX3CL1 geneCXCR3 geneCardiovascular DiseasesCardiovascular systemCarotid ArteriesCaucasiansCaucasoid RaceCell LineCellsChemokine Receptor GeneChemotaxisClinicalCohort StudiesCollaborationsComplexCoronary arteryCytoplasmic GranulesDNADNA RepairDNA SequenceDataDevelopmentDiseaseDisease OutcomeEmbolismEndothelial CellsEndotheliumEnhancersEnvironmentEnvironmental ExposureEthnic OriginEthnic groupEvolutionExocytosisFractalkineGangreneGenderGene FrequencyGenesGenetic PolymorphismGerontologyGoalsHaplotypesHealthHigh PrevalenceImmuneImmune responseImmune systemInfectious AgentInflammationInflammation MediatorsInflammatoryInflammatory ResponseInstitutesInstitutionIntermittent ClaudicationInternationalIschemiaKidney FailureLaboratoriesLeadLesionLeukocyte TraffickingLeukocytesLinkLinkage DisequilibriumLiteratureLongevityLower ExtremityMeasurementMeasuresMediatingMediator of activation proteinMethylationMissionModelingMolecular and Cellular BiologyMyocardial InfarctionMyocardiumNeighborhoodsNucleic Acid Regulatory SequencesOhioOxidative StressOxygenP-SelectinPainPatternPeripheral Vascular DiseasesPhasePhysiologic pulsePilot ProjectsPlatelet ActivationPlatelet Factor 4PlayPopulationPredispositionPrincipal InvestigatorProcessPropertyProtein IsoformsProteinsPublishingResearchResearch PersonnelRiskRisk FactorsRoleRuptureScienceSecondary HypertensionSelectinsSerumSerum MarkersSeveritiesSingle Nucleotide PolymorphismSiteSocial BehaviorSocioeconomic FactorsSocioeconomic StatusSolutionsSpecimenStagingStrokeSurrogate MarkersTestingTherapeuticThickThrombosisTissuesTravelTumor Necrosis Factor-alphaUniversitiesVariantarterial stiffnessatherogenesiscardiovascular disorder riskchemokinechemokine receptorcytokinedesignethnic differencehealth disparityhealthy agingheart rate variabilityhuman TNF proteininterestleukocyte proliferationmacrophagemonocytenovelnovel markerpromoterracial differencereceptorrenal arteryresponsesocial
中文摘要
假设社会环境暴露中的种族差异导致促炎
易患性,这反过来又会导致心血管疾病的风险增加。本研究
将使用HANDLS(多样性社区健康老龄化)的数据进行
这项研究是由美国国家老龄化研究所实验室进行的,
老年学研究中心的细胞和分子生物学。本研究旨在
将健康差异的生物学、行为学和社会学决定因素合并起来,
从社会经济地位。
英文摘要
hypothesis that race differences in socio-environmental exposures lead to a pro-inflammatory
predisposition which can in turn lead to an increased risk of cardiovascular disease. This study
will be conducted using data from the HANDLS (Healthy Aging in Neighborhoods of Diversity
across the Life Span study), a study conducted by National Institution on Aging, Laboratory of
Cellular and Molecular Biology of the Gerontology Research Center. This study is designed to
merge biological, behavior, and social determinants of health disparities without confounding
from socioeconomic status.
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会议论文
Inflammation and platelet activation
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批准号:7619999
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项目类别:
-
资助金额:$155.66万
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财政年份:2008
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负责人:Craig Fletcher
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依托单位:
Inflammation and platelet activation
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批准号:7314617
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项目类别:
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资助金额:$0.0万
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财政年份:2007
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负责人:Craig Fletcher
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依托单位:
Inflammation and platelet activation
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批准号:8072663
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项目类别:
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资助金额:$63.96万
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财政年份:--
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负责人:Craig Fletcher
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依托单位:
Inflammation and platelet activation
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批准号:8300045
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项目类别:
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资助金额:$66.21万
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财政年份:--
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负责人:Craig Fletcher
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依托单位:
海外基金