Clinical

HU CFAR研究人员具有长期的高影响力贡献历史，这些贡献来自于从工作台到床边 research. CFAR临床核心活动对这些活动的成功至关重要。 通过提供临床基础设施、临床样本和临床试验， 这些研究的关键信息;这些转化研究的组成部分要么没有资助，要么 其他支助机制提供的资金不足。随着扩展到哈佛范围的CFAR， 临床核心继续设定新的目标，并修改其使命，以最大限度地响应其成员， 特别是现在国际社会日益关注这一核心。满足HU CFAR的持续需求 我们现建议达到以下的具体目标： 为HU CFAR研究人员进行临床和基础科学提供基础设施支持 国内和国际艾滋病毒/艾滋病及其相关机会性感染的研究 化国际大 开发和提供对数据库和临床标本库的访问， 国内和国际上的艾滋病毒感染者。 支持旨在促进临床和翻译的教育和推广计划 在HU和与HU CFAR研究人员相关的国际研究中心进行研究。

HU CFAR investigators have a long history of high impact contributions stemming from bench-to-bedside research. The CFAR Clinical Core activities have been absolutely essential to the success of these HIV/AIDS research efforts at Harvard by providing the clinical infrastructure, clinical samples and clinical information critical to these studies; these components of translational research are either not funded or are only inadequately funded by other support mechanisms. With the expansion to a Harvard-wide CFAR, the Clinical Core continues to set new goals and modify its mission to be maximally responsive to its members, in particular now with an expanding international focus to this Core. To address ongoing needs of HU CFAR investigators, we now propose to accomplish the following specific aims: ¿ To provide infrastructure support for HU CFAR investigators conducting clinical and basic science research related to HIV/AIDS and its associated opportunistic infections, domestically and internationally. ¿ To develop and provide access to databases and clinical specimen repositories from wellcharacterized HIV-infected populations domestically and internationally. ¿ To support educational and outreach programs designed to facilitate clinical and translational research at HU and at international sites associated with HU CFAR investigators.