PROTEIN STRUCTURE-FUNCTION IN GASTRIC MICROBIAL PATHOGENESIS
PROTEIN STRUCTURE-FUNCTION IN GASTRIC MICROBIAL PATHOGENESIS
批准号:
7960221
负责人:
Nicholaus H Hilliard
金额:
$9.65万
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-05-01 至 2010-02-28
关键词:
AcidsBiomedical ResearchComputer Retrieval of Information on Scientific Projects DatabaseEnvironmentEventFundingGrantInstitutionMetabolic PathwayMicrobeNew MexicoPathogenesisResearchResearch PersonnelResourcesSourceStomachUnited States National Institutes of Healthbiological adaptation to stressmicrobialpathogenprotein structure functionresponse
中文摘要
这个子项目是许多研究子项目中的一个
由NIH/NCRR资助的中心赠款提供的资源。子项目和
研究者(PI)可能从另一个NIH来源获得主要资金,
因此可以在其他CRISP条目中表示。所列机构为
研究中心,而研究中心不一定是研究者所在的机构。
该项目研究了独特微生物对酸性环境的耐受性,例如在胃中发现的酸性环境。这些微生物的耐酸性反应(ATR)似乎涉及一系列事件,包括并超过了常见病原体中通常看到的事件。除了正常预期的应激反应外,代谢途径似乎也发生了显著变化
英文摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
This project investigates the tolerance of unique microbes to acidic environments such as that found in the stomach. The acid tolerance response (ATR) of these microbes appears to involve a sequence of events that both includes and surpasses that which is normally seen in common pathogens. In addition to the normally expected stress response, there appears to be a significant change in metabolic pathways
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PROTEIN STRUCTURE-FUNCTION IN GASTRIC MICROBIAL PATHOGENESIS
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批准号:7720446
-
项目类别:
-
资助金额:$9.46万
-
财政年份:2008
-
负责人:Nicholaus H Hilliard
-
依托单位:
PROTEIN STRUCTURE-FUNCTION IN GASTRIC MICROBIAL PATHOGENESIS
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批准号:7610356
-
项目类别:
-
资助金额:$6.16万
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财政年份:2007
-
负责人:Nicholaus H Hilliard
-
依托单位:
PROTEIN STRUCTURE-FUNCTION IN GASTRIC MICROBIAL PATHOGENESIS
-
批准号:7381743
-
项目类别:
-
资助金额:$6.3万
-
财政年份:2006
-
负责人:Nicholaus H Hilliard
-
依托单位:
PROTEIN STRUCTURE-FUNCTION IN GASTRIC MICROBIAL PATHOGENESIS
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批准号:7170963
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项目类别:
-
资助金额:$6.6万
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财政年份:2005
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负责人:Nicholaus H Hilliard
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依托单位:
BIOOXIDATION OF SULFUR IN MICROBIAL MODEL SYSTEMS
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批准号:6972149
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项目类别:
-
资助金额:$13.77万
-
财政年份:2004
-
负责人:Nicholaus H Hilliard
-
依托单位:
CORE--EASTERN NEW MEXICO U FACILITY
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批准号:6972142
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项目类别:
-
资助金额:$13.77万
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财政年份:2004
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负责人:Nicholaus H Hilliard
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依托单位:
海外基金