Hematopathology Diagnosis

NCI病理学实验室的血液病理学部门提供专家 血液病理学领域的诊断服务。Stefania Pittaluga博士，临床医生， 我平等地处理诊断服务职责，每个人都像工作人员一样轮流工作。 服务50%的时间。然而，由于我们收到的材料具有挑战性， 审查，以及与特定临床方案和教学会议相关的义务， 我们的临床义务远远超出了指定的服务时间。我们提供 协助诊断和分类反应性和肿瘤性淋巴增生 疾病、免疫缺陷状态和多种血液恶性肿瘤。我们提供 为国家癌症研究所的医生提供咨询和合作服务， 以及在其他研究所研究血液淋巴疾病患者的医生， 特别是NIAID、NHLBI、NHGRI和NIAMSD。我们作为助理调查员， 在NCI和其他NIH研究所进行的35项临床方案。这些协议 经常要求进行专门的测试，以阐明与疾病相关的生物标志物。 特别研究。我们每年收到2000多起咨询案件。因为 要求咨询服务对我们的时间，我们试图限制咨询， 困难或具有挑战性的案件。许多案例是由其他学术机构提交的， 诊断的不确定性，或由于几个机构之间的意见分歧。我们 经常拒绝接受我们认为属于例行性质的磋商， 建议将此类病例送往常规参考实验室。我们经常写小说。 基于这种独特的临床实践的观察，以及一些出版物， 产生了这些经验。因此，我相信我们的临床工作增强，而不是减损， from our academic学术productivity生产力.

The Hematopathology Section of the Laboratory of Pathology, NCI, offers expert diagnostic services in the field of hematopathology. Dr. Stefania Pittaluga, Staff Clinician, and I handle diagnostic service responsibilities equally, each rotating as the staff on service 50% of the time. However, because of the challenging nature of the material we receive for review, and obligations related to specific clinical protocols and teaching conferences, our clinical obligations extend well beyond the designated on-service time. We provide assistance in the diagnosis and classification of reactive and neoplastic lymphoproliferative disorders, immunodeficiency states, and diverse hematological malignancies. We provide consultative and collaborative services to physicians in the National Cancer Institute, as well as to physicians studying patients with hematolymphoid disorders in other institutes, in particular NIAID, NHLBI, NHGRI, and NIAMSD. We serve as Associate Investigators on more than 35 clinical protocols being conducted in the NCI and other NIH institutes. These protocols frequently mandate specialized testing to illuminate biological markers relevant to the particular study. We receive more than 2000 cases in consultation each year. Because of the demands that the consultation service places on our time, we try to restrict consultations to difficult or challenging cases. Many cases are submitted by other academic institutions, based on diagnostic uncertainty, or because of differences of opinion among several institutions. We regularly refuse to accept consultations that we regard to be of a routine nature, and recommend that such cases be sent to routine reference laboratories. We frequently make novel observations based on this unique clinical practice, and a number of publications have emanated these experiences. Thus, I believe our clinical work enhances, rather than detracts, from our academic productivity.