Generation of 3D root canals from two or more oral radiographs

从两张或多张口腔 X 光照片生成 3D 根管

• 批准号: 7999947
• 负责人: Alan Michael Walczak
• 金额: $ 10万
• 依托单位: IMAGINATION SOFTWARE CORPORATION
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7999947
• 关键词: American; Anatomy; Angiography; Calibration; Clinical; Computers; Data; Dental; Dental Care; Dental Offices; Dental Schools; Dentists; Diagnosis; Dimensions; Dose; Equipment; Evaluation; Failure; Frequencies; General Practitioners; Generations; Goals; Image; Image Analysis; Imagery; Interview; Letters; Methodology; Methods; Morphology; Mus; Neurosurgeon; Operative Surgical Procedures; Oral; Outcome; Patients; Philosophy; Physicians; Plant Roots; Procedures; Psyche structure; Pulp Canals; Radiation; Relative (related person); Research; Resolution; Rotation; Running; Speed; Structure; System; Technology; Three-Dimensional Image; Three-dimensional analysis; Treatment outcome; United States; Work; X-Ray Computed Tomography; base; cost; improved; innovation; neurosurgery; public health relevance; reconstruction; standard of care; success; three dimensional structure; treatment planning

DESCRIPTION (provided by applicant): About 15 million root canals are performed each year in the United States. Failure rates are about 10%, with the failed initial treatment reflecting costs in the US of over 900 million dollars per year. While there are a number of causes of the failures, one of the primary causes is the inability to assess the difficulty of the root canal's morphology, i.e., its path in three dimensions (3D). Practitioners acquire multiple radiographs to facilitate a mental estimation of this path. This estimation is limited by the fact that the 3D structures are represented in 2D images, and impairs the ability to mentally reconstruct the full morphology of the canal. 3D root canal morphology will enable improved treatment planning and improve the likelihood of success of the treatment. CT might be an option; however, CT technology is not readily available to the dentists. Because of CT's high cost, patient dose, reduced resolution, equipment size, and relative complexity, it is impractical for most dentists, in particular the general practitioner, to use CT or have such machines in their office. In the proposed research, we will evaluate the feasibility of reconstructing the 3D root canal morphology using only the radiographs that are normally acquired during a root canal procedure. Our proposed technology will provide the same the 3D root canal morphology that was previously available only using CT technology. Moreover, our technology will overcome the issues associated with CT and provide the dentist with a low cost, accurate, and easy to use product that will not require additional dose to the patient and can be run on a standard computer. In addition, we will overcome issues that could limit the quality of the generated 3D, by innovative approaches in which we take advantage of the "completing data" in the other views. To evaluate the product's feasibility, we will (1) Develop technology which allows quick and easy visualization and quantitation of 3D root canal centerlines from standard dental radiographs and allows quantitative assessment of critical structures and overcomes issues of overlap and low SNR (2) Evaluate the accuracy of the technology by comparing its results to those of micro-CT, and (3) Evaluate the impact of the developed technology on root canal procedures. Significance: With our technology, 3D root canals can be available in every dental office, using simply the radiographs they are already acquiring, at a fraction of the cost of CT, with no additional space requirements, and with the ease and speed of a few clicks of the mouse. With our technology, visualization and analysis of 3D root canals could easily become the standard of care improving dental care for millions of patients. PUBLIC HEALTH RELEVANCE: Root canal treatment decisions rely on evaluations of 2D radiographic images and mental reconstructions of the 3D root canal path. We have developed a simple and accurate method for determination of the 3D root canal path from two or more radiographic views. Its low cost, ease of use, accuracy, and clinical impact will drive expansion of 3D as the standard of care in root canal procedures positively impacting treatment decisions and treatment outcome for millions of patients.

描述（由申请人提供）：在美国，每年约有1500万根管治疗。失败率约为10%，失败的初始治疗反映了美国每年超过9亿美元的成本。虽然失败的原因有很多，但主要原因之一是无法评估根管形态的难度，即，它的三维路径（3D）。医生需要拍摄多张X光片以便于对这一路径进行心理评估。这种评估受到3D结构在2D图像中表示的事实的限制，并且削弱了在心理上重建运河完整形态的能力。3D根管形态将能够改进治疗计划并提高治疗成功的可能性。CT可能是一种选择;然而，CT技术并不容易为牙医所用。由于CT的高成本、患者剂量、降低的分辨率、设备尺寸和相对复杂性，对于大多数牙医，特别是全科医生来说，使用CT或在他们的办公室中具有这样的机器是不切实际的。在拟议的研究中，我们将评估的可行性重建三维根管形态仅使用X线照片，通常是在根管治疗过程中获得。我们提出的技术将提供相同的三维根管形态，以前只能使用CT技术。此外，我们的技术将克服与CT相关的问题，并为牙医提供低成本，准确，易于使用的产品，不需要对患者进行额外的剂量，并可以在标准计算机上运行。此外，我们将克服可能限制生成的3D质量的问题，通过创新方法，我们利用其他视图中的“完整数据”。为了评估产品的可行性，我们将（1）开发技术，使标准牙科X光片中的3D根管中心线快速简便地可视化和定量，并允许对关键结构进行定量评估，克服重叠和低SNR的问题（2）通过将其结果与micro-CT的结果进行比较，评估该技术的准确性，（3）评价新技术对根管治疗的影响。重要性：通过我们的技术，每个牙科诊所都可以使用3D根管，只需使用他们已经获得的X光照片，成本仅为CT的一小部分，没有额外的空间要求，并且只需点击几下鼠标即可轻松快速。通过我们的技术，3D根管的可视化和分析可以很容易地成为护理标准，改善数百万患者的牙科护理。 公共卫生关系：根管治疗的决策依赖于2D X线图像的评价和3D根管路径的心理重建。我们已经开发了一种简单而准确的方法来确定3D根管路径从两个或多个X线视图。其低成本、易用性、准确性和临床影响将推动3D作为根管治疗标准的扩展，对数百万患者的治疗决策和治疗结果产生积极影响。