Immune recognition of upper airway microbiota in early life as a determinant of respiratory health in children

生命早期对上呼吸道微生物群的免疫识别是儿童呼吸健康的决定因素

• 批准号: nhmrc : 1078600
• 负责人: A/Pr Belinda Hales
• 金额: $ 75.74万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/immune-recognition-upper-health-children/518592
• 关键词: Immune; recognition; upper; airway; microbiota

The study will investigate the impact of respiratory infections during infancy on lung & immune function & respiratory health between 3-7 years of age. Children were previously enrolled in a population based birth cohort study (ORChID study) which collected detailed information about the respiratory health during the first 2 years of life with daily respiratory diary & weekly nasal swab collection. In this study lung function & immune function will be assessed annually in the same children (3-7)

该研究将调查婴儿期呼吸道感染对3-7岁之间的肺部和免疫功能以及呼吸系统健康的影响。儿童之前参加了一项基于人群的出生队列研究（ORChID研究），该研究通过每日呼吸日记和每周鼻拭子采集收集了生命前2年呼吸健康的详细信息。在这项研究中，肺功能和免疫功能将每年在相同的儿童（3-7）中进行评估。