Investigation into host susceptibility and immune responses in young children with acute wheezing due to human rhinovirus group C infection

人鼻病毒C组感染引起急性喘息的幼儿宿主易感性和免疫反应调查

• 批准号: nhmrc : 1045760
• 负责人: A/Pr Belinda Hales
• 金额: $ 45.52万
• 依托单位: The University of Western Australia
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/investigation-host-susceptibility-c-infection/111785
• 关键词: Investigation; into; host; susceptibility; immune

We recently made the surprising discovery that a new viral group, human rhinovirus group C (HRV-C), causes the majority of acute asthma in children. We also found that it causes half of the acute wheezing attacks in younger children, and is the only respiratory virus associated with allergy. So, HRV-C may be the key to the relationship between allergy and asthma. The planned project will focus on whether young children who wheeze with HRV-C have related defects in their immune system.

我们最近有了一个惊人的发现，一种新的病毒群，人类鼻病毒C群（HRV-C），导致了大多数儿童急性哮喘。我们还发现，在年龄较小的儿童中，有一半的急性喘息发作是由它引起的，它是唯一与过敏有关的呼吸道病毒。因此，HRV-C可能是过敏和哮喘之间关系的关键。计划中的项目将重点关注患有HRV-C喘息的幼儿是否在免疫系统中存在相关缺陷。