Building Sustainable Community-based Research Infrastructure to Better Science (C

描述（由申请人提供）：加州大学和公益组织（一家非营利组织）的加州乳腺癌研究计划（CBCRP）提出了一个创新项目-基于社区的研究基础设施，以更好的科学（CRIBS）-以刺激基于社区的参与性研究，解决乳腺癌的环境原因和/或社会差距。我们的愿景是建立一个基础设施，包括强化培训，技术援助和网络支持的学习社区，这将导致社区/学术合作研究的环境原因和乳腺癌的社会差距，以及减少乳腺癌痛苦的解决方案。CBCRP拥有十多年资助社区/学术伙伴关系开展基于社区的参与性研究的经验，但尚未充分吸引专注于环境健康或健康差异原因的调查人员和/或社区。公益组织在与社区组织就癌症与环境的交叉科学进行对话方面有着丰富的历史，但尚未将这项工作的目标定为开展研究。拟议的项目汇集了这两个组织的优势，以实现长期目标，改变研究企业，公众健康和传统弱势群体所经历的健康差距。具体目标是：具体目标1：在学术健康中心研究人员和加州社区组织之间形成新的合作，以开展研究，重点是乳腺癌的环境原因和/或社会差距。具体目标2：通过培训和技术援助，发展可持续的基础设施，以支持社区/学术合作。具体目标3：产生有可能改变我们对乳腺癌的环境原因和/或社会差异的理解的合作研究项目。具体目标4：建立社区/学术团队的能力，以开发和提交成功的研究提案具体目标5：创建一个持续的，网络支持的社区，以支持持续的研究兴趣和持续的学习和基础设施的改进。 公共卫生相关性：据估计，高达70%的乳腺癌可能有环境原因。此外，乳腺癌发病率、死亡率和结局的差异还存在于种族、民族、性取向、残疾、阶级和社区。6该基础设施建设计划将重点关注有兴趣和参与解决乳腺癌环境原因和社会差异相关问题的社区。

DESCRIPTION (provided by applicant): The California Breast Cancer Research Program (CBCRP) of the University of California and Commonweal (a nonprofit organization) propose an innovative project - Community-based Research Infrastructure to Better Science (CRIBS) - to stimulate community-based participatory research that addresses the environmental causes of and/or social disparities in breast cancer. Our vision is to create an infrastructure consisting of intensive training, technical assistance, and a web-supported learning community that will result in the conduct of community/academic collaborative research on the environmental causes of and social disparities in breast cancer, and the solutions that will reduce the suffering from breast cancer. CBCRP has more than a decade of experience funding community/academic partnerships to conduct community-based participatory research, but has yet to fully engage investigators and/or communities focused on environmental health or causes of disparities in health. Commonweal has a rich history of engaging community organizations in dialog about the science at the intersection of cancer and the environment, but has not yet targeted this work toward the conduct of research. The proposed project brings together the strengths of these two organizations to achieve the long-term goal transforming the research enterprise, the public's health, and health disparities experienced by traditionally vulnerable populations. Specific aims are: SPECIFIC AIM 1: Form new collaborations between academic health center researchers and California community organizations to conduct research focused on environmental causes and/or social disparities in breast cancer. SPECIFIC AIM 2: Develop a sustained infrastructure to support community/academic collaborations through training and technical assistance. SPECIFIC AIM 3: Generate collaborative research projects that have the potential to transform our understanding of the environmental causes of and/or social disparities in breast cancer. SPECIFIC AIM 4: Build the capacity of the community/academic teams to develop and submit successful research proposals SPECIFIC AIM 5: Create an ongoing, web-supported community to support ongoing research interests and continual learning and infrastructure improvement. PUBLIC HEALTH RELEVANCE: It is estimated that up to 70 percent of breast cancer could have an environmental cause. Additionally disparities in breast cancer incidence, mortality, and outcomes are found in race, ethnicity, sexual orientation, disability, class, and neighborhood.6 This infrastructure building program will focus on communities interested and involved in solving the questions related to environmental causes of and social disparities in breast cancer.