fNIRS System to Further Research on Neurodevelopmental Disorders

描述（由申请人提供）：本申请寻求获得最先进的日立医疗系统ETG-4000功能性近红外光谱（fNIRS）多通道光学地形系统的支持，用于研究人类认知和社会功能的各个方面的大脑系统，以及从婴儿期早期到成年后期的整个生命周期中的典型和非典型发育。来自耶鲁大学多个学科和院系的临床和基础科学家准备使用拟议的脑成像系统，在进一步推进美国国立卫生研究院资助的转化研究项目的背景下，做出领域领先的贡献。这些研究项目涉及许多重要领域的关键问题，包括自闭症的认知神经科学、发展认知神经科学、发展精神病理学、高级认知方面，包括记忆和执行控制、视觉认知、神经成像方法发展和社会神经科学。耶鲁大学的科学家们一直走在神经成像技术的前沿，特别是当它们被应用于理解人类思维及其发展时。虽然已经取得了很大的进展，但关于典型和非典型大脑功能的基本问题仍然需要借助所要求的仪器来解决。

DESCRIPTION (provided by applicant): This proposal seeks support to acquire a state-of-the-art Hitachi Medical Systems ETG-4000 functional near infrared spectroscopy (fNIRS) multi-channel optical topography system for the study of the brain systems underpinning various aspects of human cognitive and social functioning, as well as their typical and atypical development across the lifespan, from early infancy to late adulthood. Clinical and basic scientists from multiple disciplines and departments at Yale University stand poised to use the proposed brain imaging system to make field-leading contributions in the context of furthering their National Institutes of Health-funded, translational research programs. These research programs address critical questions in a number of important areas including the cognitive neuroscience of autism, developmental cognitive neuroscience, developmental psychopathology, aspects of high-level cognition including memory and executive control, visual cognition, neuroimaging methods development, and social neuroscience. Scientists at Yale University have been at the forefront of advances in neuroimaging techniques, particularly as they are applied to understanding the human mind and its development. While much progress has been made, fundamental questions about typical and atypical brain function remain to be addressed with the help of the requested instrument.