Multi-Channel Electrochemical Measurement System

多通道电化学测量系统

基本信息

  • 批准号:
    7795013
  • 负责人:
  • 金额:
    $ 15.35万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2010
  • 资助国家:
    美国
  • 起止时间:
    2010-03-25 至 2012-12-31
  • 项目状态:
    已结题

项目摘要

DESCRIPTION (provided by applicant): We are requesting funding for the purchase of a Multi-channel Electrochemical Measurement System. Neural stimulating and recording electrodes are a major component of many implantable devices. Examples include cochlear implants and central auditory prostheses which utilize electrical neural stimulations to overcome hearing loss, and deep brain stimulation to relieve the motor symptoms of Parkinson's disease. The properties of the electrodes are an important aspect of quality control both for clinical devices and in pre-clinical animal studies. Several principal investigators at Huntington Medical Research Institutes and their collaborators are conducting NIH-funded projects using implantable electrodes, in order to develop central auditory prosthesis, and advanced deep brain and spinal cord stimulators. The proposed, state-of-the-art, true multichannel measurement system allows for multiple channels of measurements to be conducted simultaneously and independently, with up to sixteen electrodes within one array or in separate arrays. The system is expected to reduce, by a factor of sixteen, the time and labor required for the electroplating of high-charge capacity electrode material, during the fabrication of recording and stimulation electrodes. When used to characterize electrodes implanted chronically into animals, the requested instrument will also reduce the duration of anesthesia by a factor of sixteen, and may sufficiently expedite these procedures such that in some instances anesthesia will not be required. This will reduce the risk of death or medical complication for these valuable animals.
描述(由申请人提供):我们正在申请购买多通道电化学测量系统的资金。神经刺激和记录电极是许多可植入装置的主要部件。例子包括人工耳蜗和中央听觉假体,它们利用电神经刺激来克服听力损失,以及脑深部刺激来缓解帕金森病的运动症状。电极的特性是临床器械和临床前动物研究中质量控制的重要方面。亨廷顿医学研究所的几位主要研究人员及其合作者正在使用植入式电极进行NIH资助的项目,以开发中枢听觉假体以及先进的深部脑和脊髓刺激器。所提出的、最先进的、真正的多通道测量系统允许同时且独立地进行多个测量通道,其中在一个阵列内或在单独的阵列中具有多达16个电极。在制造记录和刺激电极期间,该系统预期将电镀高电荷容量电极材料所需的时间和劳动力减少十六倍。当用于表征长期植入动物体内的电极时,所要求的仪器还将麻醉持续时间缩短16倍,并且可以充分加快这些程序,使得在某些情况下不需要麻醉。这将降低这些珍贵动物的死亡或医疗并发症的风险。

项目成果

期刊论文数量(5)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Fabrication and modeling of recessed traces for silicon-based neural microelectrodes.
  • DOI:
    10.1088/1741-2552/abb9bd
  • 发表时间:
    2020-10-08
  • 期刊:
  • 影响因子:
    4
  • 作者:
    Nolta NF;Ghelich P;Ersöz A;Han M
  • 通讯作者:
    Han M
A portable neurostimulator circuit with anodic bias enhances stimulation injection capacity.
  • DOI:
    10.1088/1741-2552/ac8fb6
  • 发表时间:
    2022-10-05
  • 期刊:
  • 影响因子:
    4
  • 作者:
    Ersoz, Alpaslan;Kim, Insoo;Han, Martin
  • 通讯作者:
    Han, Martin
{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

Martin Han其他文献

Martin Han的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('Martin Han', 18)}}的其他基金

Towards Clinical Translation of Penetrating Multisite Device for Cochlear Nucleus
耳蜗核穿透性多部位装置的临床转化
  • 批准号:
    8877730
  • 财政年份:
    2015
  • 资助金额:
    $ 15.35万
  • 项目类别:
Chronically-Implantable Multisite Microelectrode Arrays
长期植入多部位微电极阵列
  • 批准号:
    8955640
  • 财政年份:
    2015
  • 资助金额:
    $ 15.35万
  • 项目类别:
Towards Clinical Translation of Penetrating Multisite Device for Cochlear Nucleus
耳蜗核穿透性多部位装置的临床转化
  • 批准号:
    9486908
  • 财政年份:
    2015
  • 资助金额:
    $ 15.35万
  • 项目类别:
Towards Clinical Translation of Penetrating Multisite Device for Cochlear Nucleus
耳蜗核穿透性多部位装置的临床转化
  • 批准号:
    9232137
  • 财政年份:
    2015
  • 资助金额:
    $ 15.35万
  • 项目类别:
Development and Evaluation of Biodegradable Neural Probes
可生物降解神经探针的开发和评估
  • 批准号:
    7388321
  • 财政年份:
    2008
  • 资助金额:
    $ 15.35万
  • 项目类别:
Development and Evaluation of Biodegradable Neural Probes
可生物降解神经探针的开发和评估
  • 批准号:
    7847760
  • 财政年份:
    2008
  • 资助金额:
    $ 15.35万
  • 项目类别:
Development and Evaluation of Biodegradable Neural Probes
可生物降解神经探针的开发和评估
  • 批准号:
    7689142
  • 财政年份:
    2008
  • 资助金额:
    $ 15.35万
  • 项目类别:

相似海外基金

The earliest exploration of land by animals: from trace fossils to numerical analyses
动物对陆地的最早探索:从痕迹化石到数值分析
  • 批准号:
    EP/Z000920/1
  • 财政年份:
    2025
  • 资助金额:
    $ 15.35万
  • 项目类别:
    Fellowship
Animals and geopolitics in South Asian borderlands
南亚边境地区的动物和地缘政治
  • 批准号:
    FT230100276
  • 财政年份:
    2024
  • 资助金额:
    $ 15.35万
  • 项目类别:
    ARC Future Fellowships
The function of the RNA methylome in animals
RNA甲基化组在动物中的功能
  • 批准号:
    MR/X024261/1
  • 财政年份:
    2024
  • 资助金额:
    $ 15.35万
  • 项目类别:
    Fellowship
Ecological and phylogenomic insights into infectious diseases in animals
对动物传染病的生态学和系统发育学见解
  • 批准号:
    DE240100388
  • 财政年份:
    2024
  • 资助金额:
    $ 15.35万
  • 项目类别:
    Discovery Early Career Researcher Award
Zootropolis: Multi-species archaeological, ecological and historical approaches to animals in Medieval urban Scotland
Zootropolis:苏格兰中世纪城市动物的多物种考古、生态和历史方法
  • 批准号:
    2889694
  • 财政年份:
    2023
  • 资助金额:
    $ 15.35万
  • 项目类别:
    Studentship
Using novel modelling approaches to investigate the evolution of symmetry in early animals.
使用新颖的建模方法来研究早期动物的对称性进化。
  • 批准号:
    2842926
  • 财政年份:
    2023
  • 资助金额:
    $ 15.35万
  • 项目类别:
    Studentship
Study of human late fetal lung tissue and 3D in vitro organoids to replace and reduce animals in lung developmental research
研究人类晚期胎儿肺组织和 3D 体外类器官在肺发育研究中替代和减少动物
  • 批准号:
    NC/X001644/1
  • 财政年份:
    2023
  • 资助金额:
    $ 15.35万
  • 项目类别:
    Training Grant
RUI: Unilateral Lasing in Underwater Animals
RUI:水下动物的单侧激光攻击
  • 批准号:
    2337595
  • 财政年份:
    2023
  • 资助金额:
    $ 15.35万
  • 项目类别:
    Continuing Grant
RUI:OSIB:The effects of high disease risk on uninfected animals
RUI:OSIB:高疾病风险对未感染动物的影响
  • 批准号:
    2232190
  • 财政年份:
    2023
  • 资助金额:
    $ 15.35万
  • 项目类别:
    Continuing Grant
A method for identifying taxonomy of plants and animals in metagenomic samples
一种识别宏基因组样本中植物和动物分类的方法
  • 批准号:
    23K17514
  • 财政年份:
    2023
  • 资助金额:
    $ 15.35万
  • 项目类别:
    Grant-in-Aid for Challenging Research (Exploratory)
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了