Enterprise Research Data Storage for Data-Intensive Computation

描述(由申请人提供)：项目摘要/摘要本S10共享仪器助学金申请申请500,000美元，用于购买辛辛那提儿童研究基金会(CCRF)的企业研究数据存储系统。提供企业数据存储系统的承诺已成为优化信息技术支持基础研究和转化性研究的一个组成部分。CCRF是辛辛那提儿童医院医学中心的研究机构，在校外研究资助金额方面跻身全国前三大儿科研究中心之列。它是辛辛那提大学医学院约500名教职员工的所在地，致力于通过研究和教育改善世界各地儿童的健康。在2008财年，CCRF雇用的教职员工收到131,619,570美元用于支持他们的研究。其中，101,660,245美元，即77%来自NIH。研究数据存储系统将整合到CCRF研究数据中心的共享资源中，并将由生物医学信息学司的教职员工管理。它允许CCRF满足快速增长的企业数据存储需求，并以不同于临床和管理存储系统所需的方式定制有关数据备份和安全的策略。这将节省成本，更灵活地支持不同类型的研究，并能够根据数据类型实施适当的安全级别。生物医学研究项目通常从许多不同的来源产生大量数据。以安全、有效的方式积累、集成和挖掘这些数据流是一项重大挑战。企业数据管理系统促进了企业的成功。将优先支持包含共享仪器并每年产生约39TB数据的研究核心，其中约80%将由NIH资助的研究项目产生。来自外部资助的研究的大多数数据必须保留5到10年，因此存储需求非常大，并随着时间的推移而增长。CCRF提议购买的数据系统是可扩展的，并允许该机构以具有成本效益的方式扩大容量。出于本申请的目的，重点将放在NIH资助的几个特定项目的需求上，尽管证明高容量企业系统合理的是多个核心和资助的研究项目的总体需求。 公共卫生相关性：辛辛那提儿童研究基金会是全国三大儿科研究中心之一，提供校外研究支持，是辛辛那提儿童医院医学中心的组成部分，辛辛那提儿童医院医学中心是辛辛那提大学医学院的主要教学附属机构。它是学院约500名教职员工的所在地，致力于通过研究和教育改善世界各地儿童的健康。投入NCRR资金改善研究数据管理将增强医学中心开展研究的能力，这是完成其使命所必需的。

DESCRIPTION (provided by applicant): Project Summary/Abstract This S10 Shared Instrumentation Grant application requests $500,000 toward the purchase of an enterprise research data storage system at Cincinnati Children's Research Foundation (CCRF). A commitment to provide an enterprise data storage system has become an integral part of optimization of IT support of basic and translational research. CCRF is the research arm of the Cincinnati Children's Hospital Medical Center and ranks among the top three pediatric research centers nationally in amount of extramural research support. It is home to approximately 500 faculty of the University of Cincinnati College of Medicine and is dedicated to improving the health of children everywhere through research and education. In FY 2008, faculty employed by CCRF received $131,619,570 to support their research. Of this total, $101,660,245 or 77% was from NIH. The research data storage system will be integrated into shared resources of the CCRF research data center and will be managed by faculty and staff of the Division of Biomedical Informatics. It permits CCRF to meet rapidly growing demands for enterprise data storage and to tailor policies with regard to data backup and security differently than is required for clinical and administrative storage systems. This will result in cost savings, greater flexibility to support different types of research, and ability to implement appropriate levels of security depending on data type. Biomedical research projects typically generate large quantities of data from many different sources. Accruing, integrating, and mining these data streams in a secure, effective way is a major challenge. Success is facilitated by enterprise data management systems. Priority will be given to support of research cores that contain shared instruments and generate approximately 39 TB of data per year, approximately 80% will be generated by NIH- funded research programs. Most data from externally funded research must be retained for periods of between 5 and 10 years, so storage requirements are very large and grow over time. The data system CCRF proposes to purchase is scaleable and permits the institution to expand capacity in a cost effective way. For the purposes of this application, focus will be upon the needs of several specific NIH-funded programs, although it is the aggregate need of multiple cores and funded research programs that justify high capacity enterprise systems. PUBLIC HEALTH RELEVANCE: The Cincinnati Children's Research Foundation ranks among the top three pediatric research centers nationally in amount of extramural research support and is an integral part of the Cincinnati Children's Hospital Medical Center, a major teaching affiliate of the University of Cincinnati College of Medicine. It is home to approximately 500 faculty of the College and is dedicated to improving the health of children everywhere through research and education. Investment of NCRR funds to improve research data anagement will strengthen the Medical Center's ability to conduct the research so ecessary to fulfill its mission.