Data management and analysis

数据管理与分析

• 批准号: 8049029
• 负责人: Charles E McCulloch
• 金额: $ 28.57万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-30 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8049029
• 关键词: Basic Science; Blood; Clinical; DNA; DNA Library; Data; Data Analyses; Data Set; Databases; Experimental Designs; Genetic; Human; Manuscripts; Monitor; Operative Surgical Procedures; Patient Recruitments; Preparation; Principal Investigator; Reporting; Research; Resources; Sampling; Source; Specimen; Structure; Tissue Banking; Tissue Banks; Tissues; data management; programs; quality assurance

Core B, the Data Management and Analysis Core (DMAC) has two primary sets of responsibilities, which may be viewed as specific aims: (a) data management, and (b) data analysis. We have extended the capabilities of Core B to act as a clearinghouse for all clinical, genetic and phenotypic data. In this fashion, Core B will effectively be the centralized group that tracks all data and its sources. The Core is available to the Principal Investigators of the other Cores and Projects for: (a) obtaining human specimens, including both DMA (blood) and surgical tissue specimens; (b) obtaining associated clinical, demographic and detailed phenotypic data associated with specimens; (c) managing and checking the flow of information into the database resources of Core B; and (d) providing datasets for statistical analysis and support. This core structure will allow for optimal coordination of the clinical and basic science research programs by providing a single centralized resource. All projects and Core C monitor and select what samples and/or data may be available for their use. Projects will use Core B to arrange obtaining specimens from either the UCSF DMA bank or the Core C surgical tissue bank. Data analysis includes biostatistical data analysis, data cleaning, quality assurance, monitoring patient recruitment and retention, and preparation of interim reports. Optimal biostatistical analysis also includes involvement in experimental design issues. Core B will also assist in preparation of manuscripts and presentations.

核心 B，数据管理和分析核心 (DMAC) 有两组主要职责，可能 被视为具体目标：(a) 数据管理，以及 (b) 数据分析。我们扩展了以下功能 核心 B 充当所有临床、遗传和表型数据的信息交换所。以这种方式，Core B 将 实际上是跟踪所有数据及其来源的集中组。 该核心可供其他核心和项目的首席研究员用于：(a) 获取人类 标本，包括 DMA（血液）和手术组织标本； (b) 获得相关的临床， 与标本相关的人口统计和详细表型数据； (c) 管理和检查流量 信息进入Core B的数据库资源； (d) 提供用于统计分析的数据集和 支持。这一核心结构将实现临床和基础科学研究的最佳协调 通过提供单一集中资源来进行程序。所有项目和Core C监控并选择哪些样本 和/或数据可供他们使用。项目将使用核心 B 安排从以下任一处获取样本 UCSF DMA 库或 Core C 手术组织库。 数据分析包括生物统计数据分析、数据清理、质量保证、监测患者 招聘和保留，以及编写临时报告。最佳生物统计分析还包括 参与实验设计问题。核心B还将协助准备手稿和 演示文稿。