Data management and analysis

数据管理与分析

• 批准号: 7663701
• 负责人: Charles E McCulloch
• 金额: $ 28.99万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-30 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7663701
• 关键词: Basic Science; Blood; Brain Vascular Malformation; Clinical; DNA; DNA Library; Data; Data Analyses; Databases; Experimental Designs; Genetic; Human; Manuscripts; Monitor; Operative Surgical Procedures; Patient Recruitments; Preparation; Principal Investigator; Reporting; Research; Resources; Sampling; Source; Specimen; Structure; Tissue Banking; Tissue Banks; Tissues; data management; programs; quality assurance

Core B, the Data Management and Analysis Core (DMAC) has two primary sets of responsibilities, which may be viewed as specific aims: (a) data management, and (b) data analysis. We have extended the capabilities of Core B to act as a clearinghouse for all clinical, genetic and phenotypic data. In this fashion, Core B will effectively be the centralized group that tracks all data and its sources. The Core is available to the Principal Investigators of the other Cores and Projects for: (a) obtaining human specimens, including both DMA (blood) and surgical tissue specimens; (b) obtaining associated clinical, demographic and detailed phenotypic data associated with specimens; (c) managing and checking the flow of information into the database resources of Core B; and (d) providing datasets for statistical analysis and support. This core structure will allow for optimal coordination of the clinical and basic science research programs by providing a single centralized resource. All projects and Core C monitor and select what samples and/or data may be available for their use. Projects will use Core B to arrange obtaining specimens from either the UCSF DMA bank or the Core C surgical tissue bank. Data analysis includes biostatistical data analysis, data cleaning, quality assurance, monitoring patient recruitment and retention, and preparation of interim reports. Optimal biostatistical analysis also includes involvement in experimental design issues. Core B will also assist in preparation of manuscripts and presentations.

核心B，数据管理和分析核心（DMAC）有两组主要职责，可以 被视为特定目的：（a）数据管理和（b）数据分析。我们扩展了 核心B充当所有临床，遗传和表型数据的交换所。以这种方式，核心B将 有效地是跟踪所有数据及其来源的集中式群体。 其他核心和项目的主要调查员可以使用核心：（a）获得人类 标本，包括DMA（血液）和手术组织标本； （b）获得相关的临床 人口统计学和详细的表型数据与标本相关； （c）管理和检查 信息核心B的数据库资源； （d）提供用于统计分析的数据集和 支持。这种核心结构将允许最佳协调临床和基础科学研究 通过提供单个集中资源来程序。所有项目和核心C监视器并选择哪些样本 和/或数据可用于使用。项目将使用核心B安排从任何一个 UCSF DMA银行或核心C手术组织库。 数据分析包括生物统计数据分析，数据清洁，质量保证，监测患者 招募和保留，以及临时报告的准备。最佳生物统计分析还包括 参与实验设计问题。核心B还将协助准备手稿，并 演讲。