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中文摘要
翻译
生物信息学/生物统计学核心(BBC核心)将使用开源Sesame软件建立实验室信息管理系统(LIMS),并建立项目数据集成网站(例如,http://toro.aecom.yu.edu/biodefense/).所有原始数据和处理后的数据都将放在网站上。患者数据将由MIS保存在Montefiore Medical Center。已建立防火墙,因此无法访问患者数据。仅向分析员提供蛋白质组学的患者和样本代码。的 生物信息学/生物统计学核心还将提供先进的研究设计,样本量合理性和定量表达的统计分析与反映各个项目的参数的咨询,并解码样本以与适当的参数相关联,例如<$HIV,<$HAART,<$IPS,<$丁丙诺啡,细胞因子表达,神经症状,迁移率等。
英文摘要
The Bioinformatics/Biostatistics Core (BBC Core) will set up a Laboratory Information Management System (LIMS) using the open source Sesame software and establish a project data integration web site (e.g.,http://toro.aecom.yu.edu/biodefense/). All primary and processed data will be placed on the web site. Patient data will be kept by MIS at Montefiore Medical Center. A firewall has been established so that patient data cannot be accessed. Only patient and sample codes for proteomics will be provided for the analysts. The Bioinformatics/Biostatistics Core will also provide consulting on advanced study design, sample size justification and statistical analysis of quantitative expression with parameters reflecting the individual projects, and decode the samples to correlate with appropriate parameters, such as ¿ HIV, ¿HAART, ¿ IPS,¿ buprenorphine, cytokine expression, neurological symptoms, transmigration rates, etc.
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Molecular basis of recognition in the Immunological Synapse
Molecular basis of recognition in the Immunological Synapse
Interdisciplinary protein engineering approach to design high affinity antibodies for flaviviruses
Interdisciplinary protein engineering approach to design high affinity antibodies for flaviviruses
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