Prevention of HIV/AIDS and STDs in Women over Fifty

描述（由申请人提供）：NOT-OD-10-034: NIH宣布通过NIH基本行为和社会科学机会网络（OppNet）为小企业创新研究和小企业转移技术研究补助金的竞争性修订申请提供恢复法案资金。摘要：美国老年妇女的艾滋病感染呈上升趋势，迫切需要针对老年妇女，特别是高危少数族裔老年妇女的文化敏感、性别特异性和年龄相适应的艾滋病预防干预措施，这一需求令人不安地未得到满足。在这一群体中，需要克服艾滋病毒/艾滋病/性病教育的耻辱和隐私障碍，加上有线老年人（包括少数民族老年人）数量的爆炸性增长，使得电子干预成为解决这一问题的理想方式，也是解决老年妇女艾滋病毒感染率的种族差异的理想方式。我们第一阶段父母补助金的总体目标是为50岁及以上的不同文化的老年妇女开发一种全面的（教育和行为的）、量身定制的、可访问的和创新的艾滋病毒/艾滋病和性病预防电子干预。根据第一阶段焦点小组的调查结果，我们现在建议修改该网站，使其符合家长补助金的设想，加入3个简短的视频，内容是一位老年妇女讨论她如何成功地解决了安全性行为的挑战。美国疾病控制与预防中心最近的研究表明，简短的视频对预防性病有积极的影响，尤其是在老年人中。第一阶段父母赠款的具体目标是：1)为文化多样化的老年妇女开发一个降低风险电子干预的原型网站，包括同行聊天室和专家提问环节；2)收集试点数据，开发个性化的在线辅导组件，并将其纳入第二阶段网站；3)评估第一阶段站点的可行性、可接受性和即时有效性，以增加知识和感知风险；4)为网站的功能扩展、评估和商业化准备第二阶段申请。在这次修订中，来自父母赠款的具体目标#1将扩展如下：1)为文化多样化的老年妇女开发一个降低风险的电子干预原型网站，包括同行聊天室、专家提问和简短的视频片段。拟议修订的具体目标是：1)研究，拍摄和编辑一个老年妇女（包括少数民族）的3个简短视频，讨论她如何成功地协商了现实生活中的安全性行为挑战2)评估网站的可行性和有效性，包括3个简短视频，以提高用户的安全性行为自我效能和艾滋病毒知识3)准备第二阶段：简短视频的包含，改进和扩展。

DESCRIPTION (provided by applicant): NOT-OD-10-034: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications for Small Business Innovation Research and Small Business Transfer Technology Research Grants through the NIH Basic Behavioral and Social Science Opportunity Network (OppNet). Abstract: HIV infection is on the rise among older women in the U.S. There is an urgent need for culturally-sensitive, gender-specific, and age-appropriate HIV prevention interventions for older women, particularly minority older women who are most at-risk - a need that is disturbingly unmet. The need to overcome stigma and privacy barriers to HIV/AIDS/STD education in this group, combined with the explosive growth in the number of wired seniors, including minority seniors, makes an e-intervention an ideal delivery method for addressing this problem, and for addressing ethnic disparities in HIV infection rates among older women. Our overall goal in the Phase 1 parent grant is to develop a comprehensive (educational and behavioral), tailored, accessible, and innovative HIV/AIDs and STD prevention e- intervention for culturally-diverse older women age 50 and over. Based on Phase 1 focus group findings, we now propose revising the site as conceived of in the parent grant to include 3 brief videos of an older woman discussing how she successfully negotiated a safe sex challenge. Recent CDC research shows brief videos can positively impact STD prevention, especially among older adults. Specific Phase 1 Aims from the parent grant are:1) Develop a prototype website for a risk reduction e- intervention for culturally-diverse older women, incorporating a peer chatroom and ask the expert segment; 2) Collect pilot data to develop an individually tailored online coaching component to be incorporated into the Phase 2 site; 3) Evaluate the feasibility, acceptability, and immediate effectiveness of the Phase 1 site for increasing knowledge and perceived risks; and, 4) Prepare for the Phase 2 application with respect to functional expansion, evaluation, and commercialization of the website. In this revision, Specific Aim #1 from the parent grant will be expanded as follows: 1) Develop a prototype website for a risk reduction e-intervention for culturally-diverse older women, incorporating peer chatroom, ask the expert, and brief video segments. Specific Aims for the proposed revision are: 1) Research, film, and edit 3 brief videos of an older woman (including minority) discussing how she successfully negotiated a real-life safe sex challenge 2) Evaluate feasibility & effectiveness of the website including 3 brief videos at increasing user safe sex self efficacy and HIV knowledge 3) Prepare for Phase 2 re: inclusion, refinement, and expansion of brief videos. PUBLIC HEALTH RELEVANCE: HIV infection rates are rising among older women, particularly African American women, creating a public health imperative for culturally-sensitive and gender-specific HIV/STD prevention interventions for older women. In Phase 1 of the parent grant, we are developing the first comprehensive (educational and behavioral), tailored, accessible, and innovative STD/HIV prevention e-intervention for culturally-diverse older women. In the proposed revision, we aim to create and test a brief video component for the website, which is based on our focus group findings, and supported by CDC research. We expect the added component will enhance the impact of the site on older women's safe sex self-efficacy and HIV knowledge, as well as contribute to consumer appeal.