Prevention of HIV/AIDS and STDs in Women over Fifty

描述(由申请人提供)：NOT-OD-10-034：NIH宣布通过NIH基本行为和社会科学机会网络(OppNet)为小企业创新研究和小企业转让技术研究补助金的竞争性修订申请提供恢复法案资金。摘要：美国老年妇女的艾滋病毒感染率正在上升。迫切需要针对老年妇女，特别是最危险的少数族裔老年妇女，采取具有文化敏感性、针对性别和年龄的艾滋病毒预防干预措施--这一需求令人担忧地没有得到满足。在这一群体中，需要克服对艾滋病毒/艾滋病/性传播疾病教育的污名和隐私障碍，再加上包括少数族裔老年人在内的联网老年人数量的爆炸性增长，使电子干预成为解决这一问题和解决老年妇女艾滋病毒感染率方面的族裔差异的理想提供方法。我们第一阶段家长资助的总体目标是为50岁及以上不同文化背景的老年妇女开发一种全面的(教育和行为)、量身定制、可获得和创新的艾滋病毒/艾滋病和性传播疾病预防电子干预措施。根据第一阶段焦点小组的调查结果，我们现在建议修改家长拨款中设想的网站，包括一名年长女性讨论如何成功谈判安全性行为挑战的3个简短视频。疾控中心最近的研究表明，简短的视频可以对性病预防产生积极影响，特别是在老年人中。父母赠款的具体第一阶段目标是：1)为不同文化背景的老年妇女开发一个减少风险电子干预的原型网站，包括一个同行聊天室，并询问专家部分；2)收集试点数据，开发一个单独定制的在线指导部分，纳入第二阶段网站；3)评估第一阶段网站的可行性、可接受性和立竿见影的效果，以增加知识和感知风险；以及，4)就网站的功能扩展、评估和商业化为第二阶段应用做准备。在这次修订中，父母赠款的具体目标1将扩大如下：1)为不同文化背景的老年妇女开发一个减少风险电子干预的原型网站，纳入同伴聊天室、询问专家和简短的视频片段。拟议修订的具体目标是：1)研究、拍摄和编辑3个老年妇女(包括少数族裔)的简短视频，讨论她如何成功地协商现实生活中的安全性行为挑战2)评估网站的可行性和有效性，包括3个简短视频，提高用户的安全性行为自我效能和艾滋病毒知识3)准备第二阶段Re：纳入、完善和扩展简短视频。 公共卫生相关性：老年妇女，特别是非裔美国妇女的艾滋病毒感染率正在上升，这使得对老年妇女采取具有文化敏感性和针对性别的艾滋病毒/性传播疾病预防干预措施成为公共卫生的当务之急。在家长赠款的第一阶段，我们正在为不同文化背景的老年妇女开发第一个全面的(教育和行为)、量身定做、可获得和创新的性传播疾病/艾滋病毒预防电子干预措施。在拟议的修订中，我们的目标是为网站创建和测试一个简短的视频组件，该组件基于我们的焦点小组调查结果，并得到疾控中心研究的支持。我们预计，增加的部分将加强网站对老年女性安全性行为自我效能和艾滋病毒知识的影响，并有助于吸引消费者。

DESCRIPTION (provided by applicant): NOT-OD-10-034: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications for Small Business Innovation Research and Small Business Transfer Technology Research Grants through the NIH Basic Behavioral and Social Science Opportunity Network (OppNet). Abstract: HIV infection is on the rise among older women in the U.S. There is an urgent need for culturally-sensitive, gender-specific, and age-appropriate HIV prevention interventions for older women, particularly minority older women who are most at-risk - a need that is disturbingly unmet. The need to overcome stigma and privacy barriers to HIV/AIDS/STD education in this group, combined with the explosive growth in the number of wired seniors, including minority seniors, makes an e-intervention an ideal delivery method for addressing this problem, and for addressing ethnic disparities in HIV infection rates among older women. Our overall goal in the Phase 1 parent grant is to develop a comprehensive (educational and behavioral), tailored, accessible, and innovative HIV/AIDs and STD prevention e- intervention for culturally-diverse older women age 50 and over. Based on Phase 1 focus group findings, we now propose revising the site as conceived of in the parent grant to include 3 brief videos of an older woman discussing how she successfully negotiated a safe sex challenge. Recent CDC research shows brief videos can positively impact STD prevention, especially among older adults. Specific Phase 1 Aims from the parent grant are:1) Develop a prototype website for a risk reduction e- intervention for culturally-diverse older women, incorporating a peer chatroom and ask the expert segment; 2) Collect pilot data to develop an individually tailored online coaching component to be incorporated into the Phase 2 site; 3) Evaluate the feasibility, acceptability, and immediate effectiveness of the Phase 1 site for increasing knowledge and perceived risks; and, 4) Prepare for the Phase 2 application with respect to functional expansion, evaluation, and commercialization of the website. In this revision, Specific Aim #1 from the parent grant will be expanded as follows: 1) Develop a prototype website for a risk reduction e-intervention for culturally-diverse older women, incorporating peer chatroom, ask the expert, and brief video segments. Specific Aims for the proposed revision are: 1) Research, film, and edit 3 brief videos of an older woman (including minority) discussing how she successfully negotiated a real-life safe sex challenge 2) Evaluate feasibility & effectiveness of the website including 3 brief videos at increasing user safe sex self efficacy and HIV knowledge 3) Prepare for Phase 2 re: inclusion, refinement, and expansion of brief videos. PUBLIC HEALTH RELEVANCE: HIV infection rates are rising among older women, particularly African American women, creating a public health imperative for culturally-sensitive and gender-specific HIV/STD prevention interventions for older women. In Phase 1 of the parent grant, we are developing the first comprehensive (educational and behavioral), tailored, accessible, and innovative STD/HIV prevention e-intervention for culturally-diverse older women. In the proposed revision, we aim to create and test a brief video component for the website, which is based on our focus group findings, and supported by CDC research. We expect the added component will enhance the impact of the site on older women's safe sex self-efficacy and HIV knowledge, as well as contribute to consumer appeal.