Prevention of HIV/AIDS and STDs in Women over Fifty

描述（由申请人提供）：NOT-OD-10-034：NIH宣布通过NIH基本行为和社会科学机会网络（OppNet）为小企业创新研究和小企业转让技术研究赠款的竞争性修订申请提供恢复法案资金。摘要：艾滋病毒感染在美国老年妇女中呈上升趋势，迫切需要对老年妇女，特别是风险最大的少数民族老年妇女进行文化敏感，性别特异性和年龄适当的艾滋病毒预防干预-这是令人不安的未满足的需求。需要克服这一群体中艾滋病毒/艾滋病/性传播疾病教育的耻辱和隐私障碍，加上有线老年人，包括少数民族老年人数量的爆炸性增长，使电子干预成为解决这一问题的理想交付方法，并解决老年妇女艾滋病毒感染率的种族差异。我们在第一阶段父母补助金的总体目标是为50岁及以上文化多样的老年妇女制定一个全面的（教育和行为）、量身定制、可获得和创新的艾滋病毒/艾滋病和性病预防电子干预措施。根据第一阶段焦点小组的调查结果，我们现在建议修改网站的设想，在父母补助金，包括3个简短的视频，一个老年妇女讨论她如何成功地谈判了安全性行为的挑战。CDC最近的研究表明，简短的视频可以对性病预防产生积极影响，特别是在老年人中。第一阶段父母赠款的具体目标是：1）为文化多样性的老年妇女开发一个减少风险的电子干预原型网站，其中包括一个同龄人聊天室和专家咨询部分; 2）收集试点数据，以开发一个个性化的在线辅导部分，并将其纳入第二阶段网站; 3）评估第一阶段网站在增加知识和感知风险方面的可行性、可接受性和即时效果; 4）为第二阶段的申请做好网站功能扩展、评估和商业化的准备。在这次修订中，来自父母赠款的具体目标#1将扩大如下：1）为文化多样性的老年妇女开发一个减少风险的电子干预原型网站，包括同伴聊天室，询问专家和简短的视频片段。建议修订的具体目标是：1）研究，电影和编辑3个老年妇女的简短视频（包括少数族裔）讨论她如何成功地应对现实生活中的安全性行为挑战2）评估网站的可行性和有效性，包括3个简短的视频，以提高用户安全性行为的自我效能和艾滋病毒知识3）为第2阶段做准备，重新：包含、细化和扩展简短的视频。 公共卫生相关性：老年妇女，特别是非裔美国妇女的艾滋病毒感染率正在上升，这就要求对老年妇女采取对文化敏感和针对性别的艾滋病毒/性传播疾病预防干预措施。在父母补助金的第一阶段，我们正在为文化多样性的老年妇女制定第一个全面的（教育和行为）、量身定制的、可获得的和创新的性病/艾滋病毒预防电子干预措施。在拟议的修订中，我们的目标是为网站创建和测试一个简短的视频组件，该组件基于我们的焦点小组调查结果，并得到CDC研究的支持。我们预计，增加的内容将加强该网站对老年妇女安全性行为自我效能和艾滋病毒知识的影响，并有助于吸引消费者。

DESCRIPTION (provided by applicant): NOT-OD-10-034: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications for Small Business Innovation Research and Small Business Transfer Technology Research Grants through the NIH Basic Behavioral and Social Science Opportunity Network (OppNet). Abstract: HIV infection is on the rise among older women in the U.S. There is an urgent need for culturally-sensitive, gender-specific, and age-appropriate HIV prevention interventions for older women, particularly minority older women who are most at-risk - a need that is disturbingly unmet. The need to overcome stigma and privacy barriers to HIV/AIDS/STD education in this group, combined with the explosive growth in the number of wired seniors, including minority seniors, makes an e-intervention an ideal delivery method for addressing this problem, and for addressing ethnic disparities in HIV infection rates among older women. Our overall goal in the Phase 1 parent grant is to develop a comprehensive (educational and behavioral), tailored, accessible, and innovative HIV/AIDs and STD prevention e- intervention for culturally-diverse older women age 50 and over. Based on Phase 1 focus group findings, we now propose revising the site as conceived of in the parent grant to include 3 brief videos of an older woman discussing how she successfully negotiated a safe sex challenge. Recent CDC research shows brief videos can positively impact STD prevention, especially among older adults. Specific Phase 1 Aims from the parent grant are:1) Develop a prototype website for a risk reduction e- intervention for culturally-diverse older women, incorporating a peer chatroom and ask the expert segment; 2) Collect pilot data to develop an individually tailored online coaching component to be incorporated into the Phase 2 site; 3) Evaluate the feasibility, acceptability, and immediate effectiveness of the Phase 1 site for increasing knowledge and perceived risks; and, 4) Prepare for the Phase 2 application with respect to functional expansion, evaluation, and commercialization of the website. In this revision, Specific Aim #1 from the parent grant will be expanded as follows: 1) Develop a prototype website for a risk reduction e-intervention for culturally-diverse older women, incorporating peer chatroom, ask the expert, and brief video segments. Specific Aims for the proposed revision are: 1) Research, film, and edit 3 brief videos of an older woman (including minority) discussing how she successfully negotiated a real-life safe sex challenge 2) Evaluate feasibility & effectiveness of the website including 3 brief videos at increasing user safe sex self efficacy and HIV knowledge 3) Prepare for Phase 2 re: inclusion, refinement, and expansion of brief videos. PUBLIC HEALTH RELEVANCE: HIV infection rates are rising among older women, particularly African American women, creating a public health imperative for culturally-sensitive and gender-specific HIV/STD prevention interventions for older women. In Phase 1 of the parent grant, we are developing the first comprehensive (educational and behavioral), tailored, accessible, and innovative STD/HIV prevention e-intervention for culturally-diverse older women. In the proposed revision, we aim to create and test a brief video component for the website, which is based on our focus group findings, and supported by CDC research. We expect the added component will enhance the impact of the site on older women's safe sex self-efficacy and HIV knowledge, as well as contribute to consumer appeal.