Project 3: Integrative Risk Assessment Methods for Engineered Nanomaterials

项目3：工程纳米材料的综合风险评估方法

• 批准号: 8066919
• 负责人: Elaine M Faustman
• 金额: $ 22.8万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-24 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8066919
• 关键词: Address; Arts; Benchmarking; Biological Markers; Budgets; Carbon Nanotubes; Ceramics; Clinical; Communication; Data; Development; Disease; Dose; Engineering; Evaluation; Goals; Gold; Heavy Metals; Hospitals; Human; In Vitro; Incentives; Information Systems; Institutes; Investigation; Link; Lung; Medical; Methods; Modeling; Molecular; Needs Assessment; Occupational; Occupations; Paper; Patients; Phase; Publishing; Quantum Dots; Relative (related person); Reporting; Research; Research Personnel; Risk; Risk Assessment; Screening procedure; Series; Solutions; Source; Structure; System; Techniques; Testing; Toxic effect; Toxicity Tests; Toxicogenomics; Toxicokinetics; United States National Academy of Sciences; Vision; Walkers; base; comparative; improved; in vivo; innovation; interest; model development; nanomaterials; nanoparticle; novel; particle; population based; predictive modeling; programs; response; toxic metal

There has been a tremendous move to publish papers calling for improved risk assessments for ENMs however in most cases few solutions and only lists of urgent data and assessment needs are provided with references. Several significant reports such as [1-3] have done an excellent job of methodically listing key avenues for research and input [1-3]. We have tiuilt on these calls for information and assessment and are proposing to develop an integrated system where data from a multitude of sources can be linked and collectively assessed in a risk assessment framework.

在发表呼吁改进环境营养物质风险评估的论文方面取得了巨大的进展，但在大多数情况下，很少有解决办法，只提供了紧急数据和评估需求的清单。一些重要的报告，如[1-3]，在系统地列出研究和投入的关键途径方面做得很好[1-3]。我们已响应这些要求提供信息和进行评估的呼吁，并建议建立一个综合系统，将来自多种来源的数据联系起来， 在风险评估框架内进行集体评估。