Project 3: Integrative Risk Assessment Methods for Engineered Nanomaterials

项目3：工程纳米材料的综合风险评估方法

• 批准号: 8066919
• 负责人: Elaine M Faustman
• 金额: $ 22.8万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-24 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8066919
• 关键词: Address; Arts; Benchmarking; Biological Markers; Budgets; Carbon Nanotubes; Ceramics; Clinical; Communication; Data; Development; Disease; Dose; Engineering; Evaluation; Goals; Gold; Heavy Metals; Hospitals; Human; In Vitro; Incentives; Information Systems; Institutes; Investigation; Link; Lung; Medical; Methods; Modeling; Molecular; Needs Assessment; Occupational; Occupations; Paper; Patients; Phase; Publishing; Quantum Dots; Relative (related person); Reporting; Research; Research Personnel; Risk; Risk Assessment; Screening procedure; Series; Solutions; Source; Structure; System; Techniques; Testing; Toxic effect; Toxicity Tests; Toxicogenomics; Toxicokinetics; United States National Academy of Sciences; Vision; Walkers; base; comparative; improved; in vivo; innovation; interest; model development; nanomaterials; nanoparticle; novel; particle; population based; predictive modeling; programs; response; toxic metal

There has been a tremendous move to publish papers calling for improved risk assessments for ENMs however in most cases few solutions and only lists of urgent data and assessment needs are provided with references. Several significant reports such as [1-3] have done an excellent job of methodically listing key avenues for research and input [1-3]. We have tiuilt on these calls for information and assessment and are proposing to develop an integrated system where data from a multitude of sources can be linked and collectively assessed in a risk assessment framework.

发表论文已采取了巨大的举动，要求对ENM进行改进的风险评估，但是在大多数情况下，仅提供了紧急数据和评估需求的清单。 [1-3]等一些重要的报告在有条不紊地列出了研究和输入的关键途径方面做得很好[1-3]。我们已经对这些信息和评估进行了调整，并建议开发一个集成系统，在该系统中可以链接来自众多源的数据，并且 在风险评估框架中集体评估。