Education/Training and Outreach Activities

教育/培训和外联活动 综合培训计划创建/扩展用于综合培训的本地和远程模块，其中可能包括研究生课程、奖学金、证书、课程和内部研讨会系列，以培养能够用物理科学和工程方法解决与癌症相关的问题的多学科学员。 纳米医学证书 癌症纳米技术是迅速发展的纳米医学学科的一部分，该学科涉及纳米技术和生物医学研究的整合。认识到这种高度跨学科的方法对基础和应用生物医学研究都有许多重要的影响，在卡罗莱纳CCNE的第一阶段，我们通过北卡罗来纳大学研究生院创建了纳米医学证书。我们计划继续提供这一证书计划。该证书适用于攻读物理或生物医学博士课程的学生以及类似领域的博士后研究员。证书课程是现有博士课程的附属课程，证书的要求将是对正常博士课程要求的补充。参加证书计划需要得到学员主要导师的批准。该计划的一个关键目标是严格和真正的跨学科，但仍然可以接触到来自非常不同背景的学生和博士后研究员。为了实现这一目标，证书计划有三个主要方面。 纳米医学课程(3个课时) 这是一门跨学科的课程，由Project 3 Pi Russell Mumper博士指导，并由包括DeSimone、周、黄、林、赞博尼和朱利亚诺在内的许多现有CCNE教员共同教授。本课程是纳米医学证书项目所有学生/研究员的必修课。该课程为具有物理、化学或生物科学背景的学生提供纳米医学跨学科领域的介绍，并强调新兴的纳米技术和生物医学应用，包括纳米材料， 纳米工程、基于纳米技术的药物输送系统、基于纳米的成像和诊断系统、纳米毒理学以及将纳米医学转化为临床研究。 纳米医学互补领域的研究轮换(3学时) 该计划中的每个学生(或研究员)都将有一名主要导师和一名共同导师。如果主要导师是一名物理科学家，那么联合导师必须是一名生物医学科学家，反之亦然。作为纳米医学证书计划的重要组成部分，学生/研究员将在合作导师的实验室中花费相当于一次研究轮换(大约三个月)的时间进行研究，并吸收应用于纳米医学的互补领域的知识框架。轮换计划将由证书计划委员会的导师、共同导师和指导导师批准。 预计联合导师将在培训过程中发挥积极作用。 课程作业(4个课时) 学生将被要求完成4个小时的课程作业，其中至少1个小时可能不计入学生的常规博士课程。这将包括至少两个课程或四个课程小时。课程分为“物理科学”、“生物科学”和“跨学科”。至少有一门课程必须在学生的主要领域之外。例如，物理博士项目的学生必须至少选修生物科学或跨学科课程中的一门课程，而生物博士项目的学生必须至少选修物理科学或跨学科课程中的一门课程。除了北卡罗来纳大学的课程外，学生们还可以选择由圣路易斯华盛顿大学提供的网络课程，该课程得到了他们的癌症纳米技术卓越中心的支持。这门课程的重点广泛，从材料科学到成像和临床应用，并将提供一个很好的机会，以获得从另一个领先机构对纳米医学的看法。学生将在华盛顿大学注册为“非机密学生”，那里有过通过谈判免除学费并向另一所学校的学生提供学分的先例。 C-CCNE月度研讨会系列 我们计划继续第一年开始的C-CCNE每月研讨会项目。这个非常成功的研讨会项目有来自当地和国内研究机构和生物技术公司的演讲者。研讨会在莱恩伯格癌症中心举行，主题从材料制造到纳米技术在癌症研究中的应用。我们将努力向实验室科学家和医生传播纳米技术的科学进步和研究机会，他们可以帮助实施翻译工作。为了鼓励参观者，我们将宣传有关这些活动的信息 通过激发北卡罗来纳大学社区和区域机构举办的研讨会。

Education/Training and Outreach Activities Integrative training Plans to create/expand local and remote modules for Integrative training that may Include graduate programs, fellowships, certifications, courses, and internal seminar series to develop multidisciplinary trainees that can tackle cancer-related problems with physical sciences and engineering approaches. Nanomedicine Certificate Cancer Nanotechnology is part of the rapidly growing discipline of Nanomedicine that involves the integrafion of nanotechnology and biomedical research. Recognizing that this highly interdisciplinary approach has many important ramifications for both basic and applied biomedical research, during the first phase of the Carolina CCNE, we created a Certificate in Nanomedicine through the UNC Graduate School. We plan to continue to offer this Certificate Program. This certificate is available to students enrolled in PhD programs in the physical or biomedical sciences, and to postdoctoral fellows in similar areas. The Certificate program is an adjunct to existing PhD programs and the requirements of the Certificate would be in addition to the normal PhD program requirements. Approval by the trainee's primary mentor is required for participation in the Certificate Program. A key goal for this Program is to be rigorous and truly interdisciplinary, but yet remain accessible to students and postdoctoral fellows from very diverse backgrounds. To attain this objective, there are three major aspects ofthe Certificate Program. Nanomedicine Course (3 course hours) This is an interdisciplinary course directed by Project 3 PI Dr. Russell Mumper and is co-taught by many current CCNE faculty including DeSimone, Zhou, Huang, Lin, Zamboni and Juliano. This course is required of all students/fellows in the Nanomedicine Certificate Program. The course offers an introduction to the interdisciplinary field of nanomedicine for students with physical, chemical or biological science background and emphasizes emerging nanotechnologies and biomedical applicafions including nanomaterials, nanoengineering, nanotechnology-based drug delivery systems, nano-based imaging and diagnosfic systems, nanotoxicoiogy, and translating nanomedicines into clinical investigation. Research Rotafion in Complementary Field of Nanomedicine (3 course hours) Each student (or fellow) in the Program will have both a primary mentor and a co-mentor. If the primary mentor is a physical scienfist then the co-mentor must be a biomedical scientist, or vice-versa. As an important part of the Nanomedicine Certificate Program, the student/fellow will spend the equivalent of one research rotation (approximately three months) in the laboratory of the co-mentor conducfing research and absorbing the intellectual framework of the complementary field as it applies to nanomedicine. Rotation plans will be approved by the mentor, co-mentor, and the guiding mentor from the Certificate Program Committee. The co-mentor will be expected to play an active role in the training process. Coursework (4 course hours) Students will be expected to complete 4 course hours of coursework at least 1 of which may not count toward the student's regular Ph.D. program. This would include a minimum of two courses or four course hours. The courses are grouped as 'Physical Sciences', 'Biological Sciences' and 'Interdisciplinary'. At least one course must be outside the student's primary field. Thus, for example, a student from a physical science Ph.D. program must take at least one course from the Biological Science or Interdisciplinary offerings, while a student from a biological Ph.D. program must take at least one course from the Physical Science or Interdisciplinary offerings. In addition to UNC-CH courses, students would be able to select a web-based course offered by Washington University in St. Louis, supported by their Center of Cancer Nanotechnology Excellence. This course has a broad focus from materials science to imaging and clinical applicafions and would provide a great opportunity to gain a perspecfive on nanomedicine from another leading Institution. Students would register as "unclassified students" at Washington University, where there is precedent for negofiafing a tuition waiver and granting credit to students from another institution. C-CCNE monthly seminar series We plan to continue the C-CCNE monthly seminar program that we started in Year 1. This very successful seminar program featured speakers from local and nafional research institufions and biotechnology firms. The seminars were held at the Lineberger Cancer Center and the topics ranged from materials fabrication to nanotechnology applications in cancer research. We will work to disseminate the scientific advances and research opportunifies of nanotechnology to both laboratory scientists as well as physicians who could help to implement translational work. In order to encourage attendance, we will promote information about these seminars through the enfire UNC community as well as regional institutions.