Immunological and respiratory effects among workers exposed to engineered nanoparticles

接触工程纳米粒子的工人的免疫和呼吸系统影响

• 批准号: nhmrc : 1023785
• 负责人: A/Pr Deborah Glass
• 金额: $ 34.24万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/immunological-respiratory-effects-engineered-nanoparticles/110303
• 关键词: Immunological; respiratory; effects; among; workers

Laboratory studies suggest that nanoparticles can easily enter the body and may cause more damage than similar, larger particles but human data are lacking. We propose to study the health of nanoparticle-exposed workers and unexposed workers, and compare biomarkers of inflammation in the blood and the respiratory system at the start and end of the shift, end of the working week and after 1 year’s further exposure to nanoparticles.

实验室研究表明，纳米颗粒很容易进入人体，可能比类似的大颗粒造成更大的伤害，但缺乏人体数据。我们建议研究纳米颗粒暴露工人和未暴露工人的健康状况，并比较在轮班开始和结束时，工作周结束时以及进一步暴露于纳米颗粒1年后血液和呼吸系统中炎症的生物标志物。