Immunomodulatory properties of amnion: from pregnancy to regenerative medicine

羊膜的免疫调节特性：从怀孕到再生医学

• 批准号: nhmrc : 1048899
• 负责人: Dr Rebecca Lim
• 金额: $ 29.76万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/immunomodulatory-properties-amnion-regenerative-medicine/112046
• 关键词: Immunomodulatory; properties; amnion; pregnancy; regenerative

Cells from the placenta have been shown to have regenerative capabilities, repairing injured tissues. In this research we aim to explore how the cells do this. In particular we will address how transplanted placental cells talk to the recipient's immune cells to better coordinate tissue repair and prevent scarring. In short, we aim to learn how these cells coordinate immune function during pregnancy to then apply this knowledge to regenerative medicine.

来自胎盘的细胞已被证明具有再生能力，修复受伤的组织。在这项研究中，我们的目标是探索细胞如何做到这一点。特别是，我们将讨论移植的胎盘细胞如何与受体的免疫细胞交谈，以更好地协调组织修复和防止疤痕。简而言之，我们的目标是了解这些细胞如何在怀孕期间协调免疫功能，然后将这些知识应用于再生医学。