Stem Cell Biology Training Program
干细胞生物学培训计划
基本信息
- 批准号:8123297
- 负责人:
- 金额:$ 17.76万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2010
- 资助国家:美国
- 起止时间:2010-08-15 至 2015-07-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
DESCRIPTION (Provided by Applicant): The investigators propose to establish a new interdisciplinary predoctoral training program in Stem Cell Biology at the University of Minnesota. The Stem Cell Institute at the University of Minnesota was established in 1999 and forms a strong hub for a broad spectrum of stem cell-based research. As the field of stem cell biology continues to rapidly expand, significantly more trained investigators are needed to address both the basic biological questions in this field, as well as translate new stem cell-based therapies to clinical medicine. The overall aim of this Stem Cell Biology Training Program is to foster the career development of outstanding predoctoral trainees to enable them to develop successful stem cell-focused research careers. To achieve this aim, this proposed training program has assembled 25 outstanding faculty members from both biomedical science and engineering departments. Research opportunities involve a full-spectrum of work on animal and human models utilizing both pluripotent stem cells as well as adult tissue-specific stem cells. Faculty in this program have expertise in the full range of disciplines that are required to advance the stem cell research field, including: basic developmental biology, molecular biology/gene therapy, cell biology, immunology, biomedical engineering, clinical and veterinary medicine, as well as bioethics. Trainees in this program will complete graduate-level courses in stem cell biology, as well as related courses such as developmental biology. A central part of the training will be to engage in a research project in stem cell biology, and participate in Stem Cell Institute research conferences, journal clubs, and symposia. Trainees will be selected by the program Steering Committee on a competitive basis. Faculty members from ten different graduate programs are to mentor a strong pool of predoctoral trainee candidates. Together, these components will provide the comprehensive training in stem cell biology required to address the need for investigators with the knowledge and expertise to move forward both the basic biological studies of stem cells and translation to novel stem cell-based clinical therapies.
RELEVANCE: Stem cell biology provides the opportunity to produce new cell-based therapies to better treat and cure a range of diseases caused by cell and tissue degeneration or injury. These diseases consist of many where there are currently no good curative options, including but not limited to diabetes, Parkinson's disease, and other neurological disorders, malignancies, and cardiovascular injury.
描述(由申请人提供):研究人员建议在明尼苏达大学建立一个新的跨学科的干细胞生物学博士前培训计划。 明尼苏达大学的干细胞研究所成立于1999年,是广泛的干细胞研究的强大中心。 随着干细胞生物学领域的持续快速发展,需要更多训练有素的研究人员来解决这一领域的基本生物学问题,并将新的基于干细胞的疗法转化为临床医学。 这个干细胞生物学培训计划的总体目标是促进优秀的博士前学员的职业发展,使他们能够发展成功的干细胞为重点的研究事业。 为了实现这一目标,这个拟议的培训计划聚集了25名来自生物医学科学和工程部门的优秀教师。 研究机会涉及利用多能干细胞以及成体组织特异性干细胞的动物和人类模型的全方位工作。 该计划的教师拥有推进干细胞研究领域所需的全方位学科的专业知识,包括:基础发育生物学,分子生物学/基因治疗,细胞生物学,免疫学,生物医学工程,临床和兽医学以及生物伦理学。 该计划的学员将完成干细胞生物学的研究生课程,以及发育生物学等相关课程。 培训的核心部分将是从事干细胞生物学的研究项目,并参加干细胞研究所的研究会议,期刊俱乐部和研讨会。 学员将由项目指导委员会在竞争的基础上选出。 来自10个不同研究生项目的教师将指导一大批博士前实习生。 这些组成部分将共同提供干细胞生物学方面的全面培训,以满足研究人员对知识和专业知识的需求,从而推进干细胞的基础生物学研究并转化为基于干细胞的新型临床疗法。
相关性:干细胞生物学提供了产生新的基于细胞的疗法的机会,以更好地治疗和治愈由细胞和组织变性或损伤引起的一系列疾病。 这些疾病包括许多目前没有良好治疗选择的疾病,包括但不限于糖尿病、帕金森病和其他神经系统疾病、恶性肿瘤和心血管损伤。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Dan S. Kaufman其他文献
The effects of human immunodeficiency virus recombinant envelope glycoprotein on immune cell functions in vitro.
人免疫缺陷病毒重组包膜糖蛋白对体外免疫细胞功能的影响。
- DOI:
- 发表时间:
1987 - 期刊:
- 影响因子:4.3
- 作者:
M. R. Shalaby;M. R. Shalaby;J. Krowka;T. J. Gregory;T. J. Gregory;S. E. Hirabayashi;S. E. Hirabayashi;Susan M. McCabe;Susan M. McCabe;Dan S. Kaufman;Dan S. Kaufman;Daniel P. Stites;Arthur J. Ammann;Arthur J. Ammann - 通讯作者:
Arthur J. Ammann
Cellular and genetic advances in analysis of hematopoietic development from human embryonic stem cells
- DOI:
10.1016/j.bcmd.2006.10.069 - 发表时间:
2007-03-01 - 期刊:
- 影响因子:
- 作者:
Petter S. Woll;C.M. Cameron;Andrew Wilber;Jonathan L. Linehan;Dan S. Kaufman - 通讯作者:
Dan S. Kaufman
HIF hits Wnt in the stem cell niche
缺氧诱导因子在干细胞龛中攻击 Wnt
- DOI:
10.1038/ncb1010-926 - 发表时间:
2010-10-01 - 期刊:
- 影响因子:19.100
- 作者:
Dan S. Kaufman - 通讯作者:
Dan S. Kaufman
Transcriptional and Functional Activity of Hemangiosarcoma Support Bone Marrow
血管肉瘤支持骨髓的转录和功能活性
- DOI:
- 发表时间:
2021 - 期刊:
- 影响因子:0
- 作者:
Jong Hyuk Kim;Ashley J. Schulte;A. Sarver;M. Angelos;M. Frantz;Colleen L. Forster;Timothy D. O’Brien;Ingrid Cornax;M. Gerard;O’Sullivan;Nuojin Cheng;M. Lewellen;L. Oseth;Sunil Kumar;Susan;Bullman;C. Pedamallu;Sagar M. Goyal;Matthew Meyerson;C. Troy;Lund;J. Alfoldi;Matthew Breen;Kerstin Lindblad;E. Dickerson;Dan S. Kaufman;Jaime F. Modiano - 通讯作者:
Jaime F. Modiano
Transcriptional and Functional Activity of Canine Hemangiosarcoma to Support
犬血管肉瘤的转录和功能活性支持
- DOI:
- 发表时间:
2021 - 期刊:
- 影响因子:0
- 作者:
Jong Hyuk Kim;Ashley J. Schulte;A. Sarver;M. Angelos;M. Aric;Frantz;Colleen L. Forster;Timothy D. O’Brien;Ingrid Cornax;M. Gerard;O’Sullivan;Nuojin Cheng;M. Lewellen;L. Oseth;Sunil Kumar;Susan;Bullman;C. Pedamallu;Sagar M. Goyal;Matthew Meyerson;C. Troy;Lund;J. Alfoldi;Kerstin Lindblad;Matthew Breen;E. Dickerson;Dan S. Kaufman;Jaime F. Modiano - 通讯作者:
Jaime F. Modiano
Dan S. Kaufman的其他文献
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{{ truncateString('Dan S. Kaufman', 18)}}的其他基金
Identification of Novel Regulators of Natural Killer Cell Activity
自然杀伤细胞活性的新型调节剂的鉴定
- 批准号:
10112574 - 财政年份:2020
- 资助金额:
$ 17.76万 - 项目类别:
Identification of Novel Regulators of Natural Killer Cell Activity
自然杀伤细胞活性的新型调节剂的鉴定
- 批准号:
10312800 - 财政年份:2020
- 资助金额:
$ 17.76万 - 项目类别:
Osteogenic Repair from Human Pluripotent Stem Cells
人类多能干细胞的成骨修复
- 批准号:
8293086 - 财政年份:2011
- 资助金额:
$ 17.76万 - 项目类别:
Osteogenic Repair from Human Pluripotent Stem Cells
人类多能干细胞的成骨修复
- 批准号:
8685947 - 财政年份:2011
- 资助金额:
$ 17.76万 - 项目类别:
Osteogenic Repair from Human Pluripotent Stem Cells
人类多能干细胞的成骨修复
- 批准号:
8490346 - 财政年份:2011
- 资助金额:
$ 17.76万 - 项目类别:
Osteogenic Repair from Human Pluripotent Stem Cells
人类多能干细胞的成骨修复
- 批准号:
9268921 - 财政年份:2011
- 资助金额:
$ 17.76万 - 项目类别:
Osteogenic Repair from Human Pluripotent Stem Cells
人类多能干细胞的成骨修复
- 批准号:
8158970 - 财政年份:2011
- 资助金额:
$ 17.76万 - 项目类别:
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