South American Prevention of HIV Research Training Program (SAPHIR)

描述（由申请人提供）：有效的艾滋病预防干预需要对特定文化背景下的行为、生物和社会传播模式进行综合分析。南美艾滋病毒预防研究项目建立在加州大学洛杉矶分校全球健康项目现有培训项目的基础上，为来自美国的发展中的研究人员提供在国际环境下全面预防艾滋病毒的密集、结构化的教育和实践研究培训项目。具体目标根据拉丁美洲艾滋病预防领域的一个重点研究课题，为美国发展中国家的研究人员提供有组织的教育和培训项目。sapir项目的学员与来自美国和拉丁美洲的研究导师配对，开发一个独立的研究项目，包括对现有数据的二次分析和原始研究方案的设计。潜在的研究课题包括与特定拉丁美洲背景下的艾滋病毒预防有关的行为、流行病学、临床和实验室问题。具体目标2。提供教学指导和互动式研讨会方案，讨论在国际环境中预防艾滋病毒的综合方法。培训计划包括每周举办一系列关于全球艾滋病毒预防关键领域的讲座和研讨会，包括讲座、期刊俱乐部、研究报告和伦理案例会议。教育方案的概念框架是基于综合艾滋病毒预防科学学科的交叉。具体目标3。建立具有各自科学专门知识领域的国际研究人员和研究中心合作网络的能力，以便为拉丁美洲的艾滋病毒预防研究制定综合方法。除了对年轻研究人员进行实践培训外，该计划的第二个目标是促进参与研究中心的机构间合作和能力建设。本专业毕业生将实现以下目标：1)掌握艾滋病综合预防的四个核心领域（流行病学、诊断、治疗和预防）的基础知识；2)完成二次数据分析，并准备相应的摘要提交给国际科学会议；3)设计独立研究子研究；4)准备一份符合加州大学洛杉矶分校人类研究受试者保护委员会规定的人类受试者研究伦理行为要求的研究方案；5)提交资助提案供同行评审，并收到书面总结陈述；6)在当地社区场地和项目学员和导师的年度会议上展示他们的研究成果。所有SAPHIR毕业生都将获得必要的知识、技能和实践经验，以获得竞争激烈的博士后培训项目的录取，并在国际艾滋病预防研究领域建立学术生涯。

DESCRIPTION (provided by applicant): Effective HIV prevention interventions require the integrated analysis of behavioral, biological, and social transmission patterns in specific cultural contexts. The South American Program in HIV Prevention Research (SAPHIR) program builds on existing training programs at the UCLA Program in Global Health to offer developing investigators from the U.S. an intensive, structured program of education and practical research training on comprehensive HIV prevention in an international environment. Specific Aim 1. To provide developing researchers from the U.S. with a structured program of education and training based on a focused research topic within the field of HIV prevention in Latin America. SAPHIR program trainees are paired with research mentors from the U.S. and Latin America to develop an independent research program incorporating both secondary analysis of existing data and design of an original research study protocol. Potential research topics include behavioral, epidemiological, clinical and laboratory issues related to HIV prevention within specific Latin American contexts. Specific Aim 2. To provide a program of didactic instruction and interactive seminars addressing integrated approaches to HIV prevention in international settings. The training program includes a weekly series of lectures and seminars on key areas of global HIV prevention, including lectures, journal clubs, research presentations, and ethics case conferences. The conceptual framework for the educational program is based on the intersection of scientific disciplines in comprehensive HIV prevention. Specific Aim 3. To build the capacity of a collaborative network of international investigators and research centers with individual areas of scientific expertise to produce integrated approaches to HIV prevention research in Latin America. In addition to practical training for young investigators, a secondary aim of the program is to promote inter-institutional collaboration and capacity-building for participating research centers. Graduates of the program will accomplish the following goals: 1) Acquire a foundation of knowledge in the four core areas of comprehensive HIV prevention (epidemiology, diagnosis, treatment, and prevention); 2) Complete a secondary data analysis and prepare a corresponding abstract for submission to an international scientific conference; 3) Design an independent research sub-study; 4) Prepare a study protocol that meets requirements for the ethical conduct of research with human subjects as defined by the UCLA Committee for the Protection of Human Research Subjects; 5) Submit a funding proposal for peer review and receive a written summary statement; and 6) Present results of their research in a local community venue and at an annual conference of program trainees and mentors. All SAPHIR graduates will acquire the exposure, skills, and practical experience necessary to gain admission to competitive post-doctoral training programs and to build an academic career in international HIV prevention research. PUBLIC HEALTH RELEVANCE: The newest generation of physician scholars recognizes the need for global approaches to HIV prevention but lacks structured opportunities for research training in international sites. A dedicated program of education and practical training in international HIV prevention studies will fill an important deficit in AIDS research.