ARESA - Advancing Research Ethics training in Southern Africa

描述(由申请者提供)：南部非洲高级研究伦理培训(ARESA)计划将通过向医疗保健和其他研究伦理专业人员提供研究生文凭/硕士水平的教育计划，并通过发展全国研究伦理委员会(REC)成员网络来促进南部非洲的负责任研究。南非斯泰伦博斯大学的生物伦理部和美国北卡罗来纳大学教堂山分校的生物伦理学中心将利用IRENSA计划建立的研究伦理学基础，通过开发研究伦理学课程，纳入卫生研究领域的广泛伦理问题，包括定性研究的伦理学、心理健康研究、土著人口的基因研究和儿科研究，从而加强和扩大非洲当地和地区的能力。课程将特别关注与研究设计和方法有关的伦理问题，以满足当地研究伦理委员会的需要，并通过强调传染病(艾滋病毒和结核病)和新出现的慢性病的研究提出的伦理挑战，反映南部非洲弱势人口面临的健康状况。每年将挑选10名南部非洲受训人员参加StellenBosch大学生物伦理学单元为期两周的强化和互动研究伦理单元，接受研究伦理委员会的审议，并完成一项实践任务。为了促进职业发展，受训人员将在ARESA教员的个别指导下，建设研究方法、手稿准备和赠款撰写方面的能力，并编制一套研究培训材料，供其本国机构使用。为了在全国范围内扩大研究伦理能力，我们将在线发布学员驱动的南非研究伦理委员会(SAREC)时事通讯，在开普敦组织ARESA年度会议，并发起成立南非研究伦理委员会协会。 与公共卫生相关：南部非洲的传染病负担很高，治疗人数众多，是涉及人类参与者的生物医学和其他研究非常受欢迎的地点。然而，该区域在道德行为和研究监管方面的地方能力仍然不完整和不发达。该计划将通过加强负责任的研究行为，并帮助维持研究机构、研究人员和社区之间的信任，为公共卫生做出贡献。

DESCRIPTION (provided by applicant): The Advancing Research Ethics training in Southern Africa (ARESA) program will promote responsible research in southern Africa by offering a postgraduate Diploma/Masters level educational program to health care and other professionals in research ethics and by developing a national network for Research Ethics Committee (REC) members. The Bioethics Unit at the University of Stellenbosch, South Africa and the Centre for Bioethics, University of North Carolina-Chapel Hill, USA will strengthen and expand local and regional African capacity using the foundation in research ethics built by the IRENSA program by developing a research ethics curriculum incorporating a broad range of ethical issues across the health research spectrum, including ethics of qualitative research, mental health research, genetic research with indigenous populations, and pediatric research. The curriculum will devote special attention to ethical issues related to research design and methodology in response to the local needs of local research ethics committees, and reflect health conditions faced by vulnerable populations in Southern Africa by emphasizing the ethical challenges raised by research on infectious diseases (HIV and TB) and emerging chronic diseases. Ten Southern African trainees per year will be selected to participate in 3 two-week intensive and interactive research ethics modules at the University of Stellenbosch Bioethics Unit, be exposed to research ethics committee deliberations, and complete a practicum assignment. To enhance career development, trainees will be individually mentored by ARESA faculty to build capacity in research methodology, manuscript preparation and grant-writing, and to develop a package of research training materials to be used at their home institutions. To expand research ethics capacity nationally, we will publish a trainee-driven South African Research Ethics Committee (SAREC) newsletter online, organize an annual ARESA conference in Cape Town, and initiate the formation of an association of South African research ethics committees. PUBLIC HEALTH RELEVANCE: With its high infectious disease burden and vast populations of treatment naove patients, Southern Africa is a highly sought after venue for biomedical and other research involving human participants. However, local capacity in the ethical conduct and regulation of research in the region remains incomplete and under-developed. This program will contribute to public health by enhancing the responsible conduct of research and by helping to maintain trust between research institutions, researchers and communities.