Protocol Specific Research Support (PSRS)

协议特定研究支持 (PSRS)

• 批准号: 8084111
• 负责人: Matthew Carabasi
• 金额: $ 9.34万
• 依托单位: THOMAS JEFFERSON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-03 至 2013-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8084111
• 关键词: Accounting; Area; Cancer Center; Clinical Research; Clinical Trials Design; Commit; Development; Financial Support; Funding; Grant; Institution; Lead; Leadership; Medical Oncologist; Modality; New Agents; Phase; Pilot Projects; Protocols documentation; Radiation; Radiation Oncologist; Research; Research Infrastructure; Research Personnel; Research Support; Scientist; Surgical Oncologist; Testing; Therapeutic; data management; experience; innovation; member; novel; programs

PROTOCOL SPECIFIC RESEARCH The Protocol Specific Research program provides data management and other infrastructure support of novel clinical trials designed and implemented by Kimmel Cancer Center members. These trials are innovative, early phase (I or II), and/or pilot studies testing concepts that are likely to lead to expanded, externally funded studies. Since the last grant submission, the investigators at the Kimmel Cancer Center have been committed to the development of investigator-initiated trials. Institutional funds cover experienced support staff for these trials. Funds are being requested to provide financial support for additional clinical research coordinators for the planned investigator initiated trials (IIT). The area of greatest emphasis has been in the development of innovative "first-in-man" trials of new agents, in conjunction with therapeutic radiation. These trials are conducted with multi-disciplinary leadership including radiation oncologists, medical oncologists, surgical oncologists, and translational scientists. Over the last 6 years, the number of these trials has increased from 3 to 9 active trials. The 9 multi-modality IIT currently open accounted for 60% of the cancer center therapeutic accrual during 2006. As of April, 2007, there are 3 multi-modality IIT trials under active development. The institution will continue to provide funds to support staff for these IIT trials.

方案特定研究 协议特定研究计划提供数据管理和其他基础设施支持， Kimmel癌症中心成员设计和实施的新临床试验。这些试验 创新的、早期阶段（I或II）和/或试点研究，测试可能导致扩大的概念， 外部资助的研究。自从上次拨款申请以来，Kimmel癌症中心的研究人员 一直致力于开发自动启动的试验。机构资金覆盖经验丰富的 这些审判的支助人员。目前正在申请资金，为更多的临床研究提供财政支持。 计划的研究者启动试验（IIT）的研究协调员。最强调的领域是 一直在开发创新的“首次在人”试验的新药物，结合治疗 辐射这些试验是在多学科领导下进行的，包括放射肿瘤学家， 医学肿瘤学家、外科肿瘤学家和转化科学家。在过去的六年里， 这些审判从3项增加到9项。目前开办的9家多模式IIT占60% 2006年癌症中心的治疗费用截至2007年4月，共有3项多模式IIT试验 积极发展中。该机构将继续提供资金，以支持这些IIT试验的工作人员。