Tissue Procurement Facility

9.7.1摘要：纸巾采购设施 导演：艾米·斯库比茨 组织采购机构(以下简称TPF)的任务是从以下机构采购样本。 患者支持明尼苏达大学的基础、翻译和临床癌症研究人员 目前由国家同行评审机构资助的癌症中心。我们的目标是开发一种 病人来源样本的储存库，包括保存完好的恶性肿瘤和良性肿瘤样本， 罕见的肿瘤，器官与正常组织匹配，如有可能，与正常组织无关。TPF是一种 集中资源控制：组织样本处理、存储、质量控制、 分发、患者同意和记录维护。TPF拥有办公室和实验室，这是。 ，与外科病理学冻结的卫星区域和明尼苏达大学的手术室相邻 医疗中心，美景镇。TPF有两个液氮冷冻机和一个80摄氏度的冷冻机，带氧。 )。传感器和警报系统。研究人员可以按小时使用Acryostate和Microtome。这个 TPF与外科病理学部门的活动无缝合作，这样废物组织就可以 加工方法：(A)在液氮中冷冻；(B)嵌入低温保鲜剂中，然后在-80℃下冷冻；(C)。 固定在福尔马林中，然后包埋在石蜡中；及(D)作为新鲜组织保存以供立即使用：我们 确保所有患者在我们采购废物组织之前签署同意书，这可能 。包括实体肿瘤、正常实体组织、血液、尿液、唾液和腹水。此外，我们还“习惯” 设计“获取组织标本的方式，以满足每个癌症患者的个性化要求 中心成员。为了满足癌症中心成员日益增长的组织需求，我们计划 扩大我们的服务以获取细胞学标本，(包括胰腺细针抽吸标本， 胸水、腹水)。我们还将为研究人员提供组织微阵列并进行激光治疗。 标本的捕获显微解剖和免疫组织化学染色

9.7.1 ABSTRACT: TISSUE PROCUREMENT FACILITY Director: Amy Skubitz .. ¿ The mission of the Tissue Procurement Facility (hereafter abbreviated TPF) is to procure samples from¿ . patients in support of basic, translational; and clinical cancer researchers at the University of Minnesota ' Cancer Center who are currently funded by national peer-reviewed agencies. Our goal is to develop a repository of patient-derived specimens including well preserved samples of malignant and benign tumors, rare tumors, organ matched normal tissue, and when possible, unrelated normal tissues. The TPF is a centralized resource thatcontrols for: standardization of tissue sample processing, storage, quality control, distribution, patient consent, and record maintenance. The TPF has office and laboratory space which is . , contiguous with Surgical Pathology's frozen satellite area and operating rooms of the University of Minnesota MedicalCenter, Fairview. The TPF has two liquid nitrogen freezers and one -80C freezer,with aooxygen ¿. sensor and an alarm system. Acryostatand microtome areavailable for hourly .usage by researchers. The TPF works seamlessly with the activities of 'the Surgical Pathology Division, such that waste tissues are ¿ processed by: (a) freezing in liquid nitrogen; (b) embedding in a cryopreservative, then freezing at -80¿C; (c) . fixing in formalin, then embedding in paraffin; and (d) maintaining as fresh tissue foYimmediate use: We ensure that all patients sign our consent form prior to our procurement of their waste tissue, which may . include solid tumors, normal solid tissue, blood, urine, saliva, and ascites fluid. In addition, we "custom design" the way tissue specimens are procured in order to fulfill the Individual requests of each of the Cancer Center members. In order to meet the increasing tissue needs of Cancer Center members, we plan to expand our services to procure cytology specimens, (including pancreatic fine needle aspiration specimens, pleural fluid, and ascites fluid). Wewill also provide researchers with tissue microarrays and perform laser, . capture microdissection and immunohistochemical staining of samples