Vision In Preschoolers - Hyperopia in Children (VIP-HIP)

学龄前儿童视力 - 儿童远视 (VIP-HIP)

• 批准号: 8026170
• 负责人: MARJEAN T KULP
• 金额: $ 78.86万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2014-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8026170
• 关键词: Amblyopia; Asthenopia; Attention; Behavior; Child; Clinical Practice Guideline; Development; Epidemiologic Studies; Evaluation; Glass; Goals; Guidelines; Headache; Hyperopia; Investigation; Link; Nursery Schools; Ophthalmic examination and evaluation; Outcome Measure; Parents; Performance; Policies; Preschool Child; Randomized Clinical Trials; Reading; Refractive Errors; Schools; Strabismus; Testing; Vision; Vision Screening; Visual Acuity; early childhood; evidence base; improved; literacy; primary outcome; response; visual-motor integration

DESCRIPTION (provided by applicant): Our prior NEI multicenter Vision in Preschoolers (VIP) studies identified the most effective tests for preschool vision screening, and federal initiatives are currently underway to increase the number of preschool children receiving vision screening and eye examinations. Clinical practice guidelines for children detected with amblyopia or strabismus are clear, but no evidence-based management guidelines are available for managing the many more children detected who have moderate to large hyperopic refractive errors without amblyopia or strabismus. The requirement for accommodation in the uncorrected hyperope may result in eyestrain, headache, intermittent blur and difficulty attending at near, leading to subsequent reading and school performance problems. Several studies have linked hyperopia and reading ability, but large-scale investigations have not been conducted in preschool children. Thus, the benefit of detecting children with moderate to large hyperopic refractive errors via vision screening and examining them for prescription of glasses is controversial. The proposed Vision In Preschoolers - Hyperopia In Preschoolers (VIP - HIP) cross- sectional multi-center epidemiological study will answer the following question: Do uncorrected hyperopic (e3D to <6D) 4 or 5yearold children without strabismus or amblyopia perform worse on a battery of educational tests than do comparable emmetropic children? The primary outcome measure will be performance on an assessment of literacy, the Test of Preschool Early Literacy (TOPEL). Results on literacy will be supplemented with results on assessments of attention (LeiterR sustained attention subtest), visual motor integration (Beery-Buktenica Developmental Test of Visual-Motor Integration, 5th Edition [BEERY" VMI]), and behavior and development as provided by parental assessment (Connors Early Childhood [Connors EC] and the Parents' Evaluation of Development Status [PEDS]). The relation between moderate hyperopia and early educational performance will be further investigated by 1) evaluating the association of hyperopia and visual function (visual acuity at distance and near, ocular alignment, stereoacuity), and 2) evaluating accommodative response as a mechanism responsible for any relations found between hyperopia and academic performance. The proposed VIPHIP study will have substantial impact on the understanding of any effects of uncorrected hyperopia on early educational performance and visual function. The results of the study will determine the need for and relevance of a full-scale randomized clinical trial (RCT) to determine whether refractive correction in preschool improves any deficit in performance on early educational tests. The results will also have implications for vision screening policy and prescribing guidelines for glasses. PUBLIC HEALTH RELEVANCE: The proposed Vision in Preschoolers - Hyperopia in Preschoolers (VIP - HIP) cross-sectional multi-center epidemiological study will have substantial impact on the understanding of any effects of uncorrected hyperopia on early educational performance and visual function. The results of the study will determine the need for and relevance of a full-scale randomized clinical trial to determine whether refractive correction in preschool improves any deficit in performance on early educational tests.

描述（由申请人提供）：我们先前在学龄前儿童（VIP）研究中的NEI多中心愿景确定了对学龄前视觉筛查的最有效测试，目前正在进行联邦倡议，以增加接受视力筛查和眼科检查的学龄前儿童的数量。对于弱视或斜视检测到的儿童的临床实践指南很明确，但是没有证据基于证据的管理指南可用于管理更多的儿童，他们在没有弱视或斜视的情况下患有中度至大型远视屈光不正。在未经校正的Hyperope中进行住宿的要求可能会导致眼神，头痛，间歇性的模糊和近距离出现，从而导致随后的阅读和学校表现问题。几项研究已将远视和阅读能力联系起来，但是在学龄前儿童中尚未进行大规模研究。因此，通过视力筛查和检查玻璃处方的情况下，检测患有中度至大型远视折射率的儿童的好处是有争议的。学龄前儿童的拟议视觉 - 学龄前儿童（VIP -HIP）横截面多中心流行病学研究将回答以下问题：未经校正的远视（E3D至<6d）4或5年儿童（没有斜向的儿童）在没有斜杆或amblyplyopia的教育测试中比可比较的儿童更差吗？主要结果指标将是评估扫盲，早期扫盲的测试（TOPEL）的表现。素养的结果将补充有关注意的评估结果（Leiterr持续注意力测试），视觉运动整合（Beery-Buktenica的发展测试，视觉运动整合的发展测试，第五版[Beery“ VMI]）[BEERY“ VMI]）以及由父母评估所提供的（Connors幼儿期间的早期效果[Connors ec and persmutiation Interial Intival Interional Interriation Interial Interiation Interral Interiation Interral Interiation Intral Intival Intival Intival Intifation Intraliation Intraliation [Connors contion''通过1）评估远视和视觉功能的关联（距离和附近的视觉敏锐度，眼对准，立体状态），2）评估可容纳的响应，作为对拟议的胃部绩效之间的任何关系的一种机制，将对未经验证的Hyperopia对早期绩效的任何影响都具有实质性影响。随机临床试验（RCT）确定学前班中的屈光度校正是否可以改善早期教育测试的表现不足。 公共卫生相关性：学龄前儿童的拟议愿景 - 学龄前儿童（VIP -HIP）横截面多中心流行病学研究将对对未经校正的远视对早期教育表现和视觉功能的任何影响的理解产生重大影响。该研究的结果将确定一项全尺度随机临床试验的需求和相关性，以确定学前班中的屈光纠正是否会改善早期教育测试的表现赤字。