Vision In Preschoolers - Hyperopia in Children (VIP-HIP)

学龄前儿童视力 - 儿童远视 (VIP-HIP)

• 批准号: 8536484
• 负责人: MARJEAN T KULP
• 金额: $ 33.56万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2014-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8536484
• 关键词: Amblyopia; Asthenopia; Attention; Behavior; Child; Clinical Practice Guideline; Development; Epidemiologic Studies; Evaluation; Glass; Goals; Guidelines; Headache; Hyperopia; Investigation; Link; Nursery Schools; Ophthalmic examination and evaluation; Outcome Measure; Parents; Performance; Policies; Preschool Child; Randomized Clinical Trials; Reading; Refractive Errors; Schools; Strabismus; Testing; Vision; Vision Screening; Visual Acuity; early childhood; improved; literacy; primary outcome; response

Our prior NEI multicenter Vision In Preschoolers (VIP) studies identified the most effective tests for preschool vision screening, and federal initiatives are currently underway to increase the number of preschool children receiving vision screening and eye examinations. Clinical practice guidelines for children detected with amblyopia or strabismus are clear, but no evidencebased management guidelines are available for managing the many more children detected who have moderate to large hyperopic refractive errors without amblyopia or strabismus. The requirement for accommodation in the uncorrected hyperope may result in eyestrain, headache, intermittent blur and difficulty attending at near, leading to subsequent reading and school performance problems. Several studies have linked hyperopia and reading ability, but largescale investigations have not been conducted in preschool children. Thus, the benefit of detecting children with moderate to large hyperopic refractive errors via vision screening and examining them for prescription of glasses is controversial. The proposed Vision In Preschoolers - Hyperopia In Preschoolers (VIP - HIP) cross- sectional multi-center epidemiological study will answer the following question: Do uncorrected hyperopic (e3D to <6D) 4 or 5yearold children without strabismus or amblyopia perform worse on a battery of educational tests than do comparable emmetropic children? The primary outcome measure will be performance on an assessment of literacy, the Test of Preschool Early Literacy (TOPEL). Results on literacy will be supplemented with results on assessments of attention (LeiterR sustained attention subtest), visualmotor integration (BeeryBuktenica Developmental Test of VisualMotor Integration, 5th Edition [BEERY" VMI]), and behavior and development as provided by parental assessment (Connors Early Childhood [Connors EC] and the Parents' Evaluation of Development Status [PEDS]). The relation between moderate hyperopia and early educational performance will be further investigated by 1) evaluating the association of hyperopia and visual function (visual acuity at distance and near, ocular alignment, stereoacuity), and 2) evaluating accommodative response as a mechanism responsible for any relations found between hyperopia and academic performance. The proposed VIPHIP study will have substantial impact on the understanding of any effects of uncorrected hyperopia on early educational performance and visual function. The results of the study will determine the need for and relevance of a fullscale randomized clinical trial (RCT) to determine whether refractive correction in preschool improves any deficit in performance on early educational tests. The results will also have implications for vision screening policy and prescribing guidelines for glasses.

我们先前的学龄前儿童NEI多中心视觉(VIP)研究发现 最有效的学龄前视力筛查测试和联邦倡议是 目前正在增加接受视力检查的学龄前儿童的数量 筛查和眼睛检查。儿童临床实践指南 弱视或斜视的检测是明确的，但没有证据 管理指南可用于管理更多的儿童 检测出哪些人有中度到重度的远视屈光不正 弱视或斜视。对居所的要求 未经矫正的过敏症可能会导致眼睛疲劳、头痛、间歇性模糊和 就近学习有困难，导致随后的阅读和上学 性能问题。几项研究已将远视与阅读联系起来 能力，但还没有在学龄前进行大规模的调查 孩子们。因此，检测中度到重度远视儿童的好处 通过视力筛查和检查屈光不正的处方 眼镜是有争议的。 学龄前儿童远视的建议视觉(VIP-HIP)交叉 分段多中心流行病学研究将回答以下问题：Do 未矫正远视(E3D至&lt；6D)4或5岁儿童无斜视或 弱视在一系列教育测试中的表现比可比的差 正视儿童？主要结果衡量标准将是 读写能力评估，学龄前早期读写能力测试(TOPEL)。结果显示 识字率将得到注意力评估结果的补充(LeiterR 持续注意分测验)、视觉运动整合(BeeryBuktenica Development 可视化电机集成测试，第5版[Beery“VMI])，以及行为和 父母评估提供的发展(康纳斯幼儿[康纳斯 和父母发育状况评估[PEDS])。 中度远视与早期教育成绩的关系将是 进一步研究：1)评估远视与视觉功能的关系 (远近视力、眼线、立体视敏度)，以及2)评估 适应性反应作为一种机制，负责处理发现的 远视和学习成绩。 拟议的VIPHIP研究将对理解任何 裸眼远视对早期学习成绩和视功能的影响。 这项研究的结果将决定全面量表的必要性和相关性 随机临床试验(RCT)确定学龄前儿童是否进行屈光矫正 改善早期教育测试中的任何不足之处。结果也将是 对视力筛查政策和眼镜处方指南有影响。