BRAiN: Building Research Achievement in Neuroscience

BRAiN：建立神经科学研究成果

• 批准号: 8150928
• 负责人: Diego Restrepo
• 金额: $ 48.23万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-30 至 2015-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8150928
• 关键词: Academic achievement; Academy; Achievement; African American; Age; Behavior; Behavioral; Behavioral Sciences; Biology; Biomedical Research; Categories; Colorado; Development; Doctor of Philosophy; Education; Education Projects; Educational Curriculum; Enrollment; Evaluation; Faculty; Funding; Goals; Grant; Head; Hispanic Americans; Hispanics; Home environment; Institution; Institutional National Research Service Award; Internet; Investigation; Knowledge; Leadership; Life; Measurable; Medical; Mentors; Mentorship; Minority-Serving Institution; Native Americans; Neurosciences; Neurosciences Research; New Mexico; Outcome; Population Heterogeneity; Postdoctoral Fellow; Program Evaluation; Psychology; Pueblo Race; Recruitment Activity; Reporting; Research; Research Training; Resources; Science; Series; Site; Societies; Students; Surveys; Training; Training Programs; Underrepresented Minority; United States National Institutes of Health; Universities; Utah; base; brain behavior; career; college; disability; experience; graduate student; knowledge base; meetings; member; pre-doctoral; programs; public health relevance; skills; symposium; translational neuroscience

DESCRIPTION (provided by applicant): Building Research Achievement in Neuroscience (BRAiN): Student Training through Institutional Partnerships will bridge the Neuroscience research participation gap by preparing diverse undergraduates in the Rocky Mountain and Southwest Region for successful entry to Neuroscience Ph.D. programs. BRAiN unites preexisting formal research and education programs at diverse institutions: the Neuroscience Graduate Program at the University of Colorado Denver in the Anschutz Medical Campus (NSP at UCD-AMC), home to a T32 Neuroscience Training Grant; the RISE to Excellence biomedical research education program at New Mexico State University (NMSU), a Hispanic serving minority institution; and the undergraduate Brain and Behavior program of the Department of Psychology at the University of Colorado Denver downtown campus (UCD-DT). BRAiN aspires to expand through developmental partnerships with Colorado State University- Pueblo and other colleges in the region. Broad participation in the Ph.D. Neuroscience/Behavior pipeline will be enabled through pursuit of three specific aims: (1) Recruitment of 67 BRAiN Scholars from diverse demographic groups that are nationally underrepresented in biomedical and behavioral neuroscience research; (2) Development of the Neuroscience/Behavior research expertise and professional skills of BRAiN Scholars; (3) Retention of BRAiN Scholars in Neuroscience/Behavior research through enrolment in postgraduate programs. BRAiN will provide intensive training that combines mentored independent research with student development of a rich knowledge base in Neuroscience core concepts. Curriculum integration will be achieved through a common Neuroscience Seminar Series and a Neuroscience Core Course. Emphasis will be placed on enhancement of mentorship skills through activities such as the Neuroscience Mentor Academy where faculty will meet to discuss student training, program evaluation, and curriculum reform. Taken together, proposed activities will provide an integrated research and professional development experience across multiple sites that leverages 21st century resources for scientific investigation and is responsive to practical aspects of contemporary student life. PUBLIC HEALTH RELEVANCE: Building Research Achievement in Neuroscience (BRAiN): Student Training through Institutional Partnerships will fulfill the goal of RFA-MH-10-070 (http://grants.nih.gov/grants/guide/rfa-files/RFA-MH-10-070.html) to encourage and prepare undergraduate students from diverse backgrounds to enter Ph.D. degree programs in the Neurosciences. This is an important goal because as stated in the RFA, demographic profiles from the NSF and reports from the National Academies reveal the national need for developing a well-trained workforce in biomedical and behavioral sciences and the continuing importance of developing a strong, vital scientific workforce whose diversity reflects that of our nation.

描述（由申请人提供）：建立神经科学研究成果（BRAIN）：通过机构合作伙伴关系的学生培训将通过为落基山脉和西南地区的不同本科生成功进入神经科学博士学位，弥合神经科学研究参与差距。程序. BRAiN联合了不同机构先前存在的正式研究和教育项目：位于安舒茨医学校区的科罗拉多丹佛大学的神经科学研究生项目（UCD-AMC的NSP），T32神经科学培训补助金的所在地;新墨西哥州州立大学（NMSU）的卓越生物医学研究教育计划，这是一个西班牙裔服务少数民族机构;以及科罗拉多大学丹佛市中心校区心理学系的本科生大脑和行为项目（UCD-DT）。BRAIN渴望通过与科罗拉多州立大学-普韦布洛和该地区其他学院的发展伙伴关系来扩大规模。广泛参与Ph.D.神经科学/行为管道将通过追求三个具体目标来实现：（1）从全国生物医学和行为神经科学研究代表性不足的不同人口群体中招募67名BRAiN学者;（2）发展神经科学/行为研究专业知识和BRAiN学者的专业技能;（3）通过研究生课程的招生保留BRAiN学者在神经科学/行为研究。BRAIN将提供强化培训，将指导独立研究与学生在神经科学核心概念中丰富知识基础的发展相结合。课程整合将通过一个共同的神经科学研讨会系列和神经科学核心课程实现。重点将放在加强导师技能，通过活动，如神经科学导师学院，教师将开会讨论学生培训，计划评估和课程改革。总的来说，拟议的活动将提供跨多个站点的综合研究和专业发展经验，利用21世纪世纪的科学调查资源，并对当代学生生活的实际方面作出反应。 公共卫生相关性：建立神经科学研究成果（BRAiN）：通过机构合作伙伴关系进行学生培训将实现RFA-MH-10-070（http：//grants.nih.gov/grants/guide/rfa-files/RFA-MH-10-070.html）的目标，以鼓励和准备来自不同背景的本科生进入博士学位。神经科学学位课程。这是一个重要的目标，因为正如RFA中所述，NSF的人口概况和国家科学院的报告揭示了国家需要在生物医学和行为科学领域培养训练有素的劳动力，以及培养一支强大的重要科学劳动力的持续重要性，其多样性反映了我们国家的多样性。

项目成果

Membrane Docking of the Synaptotagmin 7 C2A Domain: Electron Paramagnetic Resonance Measurements Show Contributions from Two Membrane Binding Loops.

• DOI: 10.1021/acs.biochem.5b00421
• 发表时间: 2015-09-22
• 期刊: Biochemistry
• 影响因子: 2.9
• 作者: Osterberg JR;Chon NL;Boo A;Maynard FA;Lin H;Knight JD
• 通讯作者: Knight JD

Monoacylglycerol lipase inhibition alters social behavior in male and female rats after post-weaning social isolation.

• DOI: 10.1016/j.bbr.2017.12.038
• 发表时间: 2018-04-02
• 期刊: Behavioural brain research
• 影响因子: 2.7
• 作者: Fontenot J;Loetz EC;Ishiki M;Bland ST
• 通讯作者: Bland ST

Brain regional differences in social encounter-induced Fos expression in male and female rats after post-weaning social isolation.

• DOI: 10.1016/j.brainres.2015.11.006
• 发表时间: 2016-01-01
• 期刊: Brain research
• 影响因子: 2.9
• 作者: Ahern M;Goodell DJ;Adams J;Bland ST
• 通讯作者: Bland ST

A novel escapable social interaction test reveals that social behavior and mPFC activation during an escapable social encounter are altered by post-weaning social isolation and are dependent on the aggressiveness of the stimulus rat.

一项新颖的逃避社会互动测试表明，在逃避的社会遭遇期间的社会行为和MPFC激活会因断奶后的社会隔离而改变，并且取决于刺激大鼠的侵略性。

• DOI: 10.1016/j.bbr.2016.09.025
• 发表时间: 2017-01-15
• 期刊: BEHAVIOURAL BRAIN RESEARCH
• 影响因子: 2.7
• 作者: Goodell, Dayton J.;Ahern, Megan A.;Baynard, Jessica;Wall, Vanessa L.;Bland, Sondra T.
• 通讯作者: Bland, Sondra T.