Neurology Research Education and Mentorship Program

描述（由申请人提供）：越来越需要医生-科学家将基础神经科学的发展转化为临床护理的改善。然而，对于临床研究者来说，获得基础、临床和转化研究的资金变得越来越困难。神经病学学员需要在其职业生涯的形成阶段保护研究时间和优秀的指导，以便能够成功地竞争指导职业（K奖）和其他赠款。哥伦比亚大学神经病学系一直是将研究纳入住院医师培训经验的强烈支持者。自1979年以来，该部门有一个临床神经科学培训计划（T32 NS 07155），为PGY 4居民和第一年的研究员提供资金，以学习研究方法和进行研究的T32。自2002年以来，我们有一个居民研究导师计划，将居民与教师导师配对进行研究项目。然而，这些举措受到了限制，因为对住院医师的临床要求越来越高，这使得他们无法参与T32机制所要求的2年全职工作，并且缺乏系统的方法来提供集中的、连续的专用研究时间来从事研究项目。目前的提案描述了一项计划，以正式的居民研究经验，每年至少有1名居民谁被认为是有特殊的承诺，成为一个独立的基础，临床或翻译神经科学研究人员。重点将是一个实用的，导师指导的研究经验，有限的课堂时间，和居民谁参加这个计划将处于最佳位置，以竞争指导职业奖（K奖）在2年的培训经验桥接居住和奖学金完成。项目主任Elkind博士拥有独立的NIH资金，以及经验指导和审查赠款，该计划的教师都是经验丰富的基础，临床或翻译研究人员。该计划将主要通过学员获得K 08和K23奖项的成功，以及学术职业安置和出版物的生产力进行评估。 公共卫生相关性：神经系统疾病，包括中风、痴呆、癫痫和神经退行性疾病，是常见的，并造成严重的发病率和死亡率负担。近年来，实验室和临床神经科学取得了显着进展，现在有越来越多的作用，为医生科学家在神经科学的发展转化为临床护理的改善。在研究方法的职业形成阶段培训年轻的神经科医生，并鼓励他们将研究视为一种职业，将增加致力于成功的医学科学家的数量。该研究教育计划将为有才华的神经病学居民提供发展研究技能的机会，这些技能很有可能减轻神经疾病的负担。

DESCRIPTION (provided by applicant): There is a growing need for physician-scientists to translate developments in basic neuroscience into improvement in clinical care. Obtaining funding for basic, clinical, and translational research, however, has become increasingly difficult for clinician investigators. Neurology trainees require protected research time and excellent mentoring during the formative stages of their careers to be able to compete successfully for mentored career (K awards) and other grants. The Columbia University Neurology Department has been a strong proponent of incorporating research into the training experience of residents. Since 1979, the department has had a T32 for a Clinical Neuroscience Training Program (T32 NS07155), which provided funding for PGY4 residents and first year fellows to learn research methodology and conduct research. Since 2002, we have had a Resident Research Mentorship Program that pairs residents with faculty mentors to work on a research project. These initiatives have been limited, however, by increasing clinical requirements for residents that preclude their participation in 2 year full time commitment required by the T32 mechanism, and by the absence of a systematic approach to providing a concentrated, contiguous block of dedicated research time to work on a research project. The present proposal describes a plan to formalize the resident research experience for at least 1 resident annually who is considered to have exceptional promise to become an independent basic, clinical, or translational neuroscience researcher. The focus will be on a practical, mentor-directed research experience, with limited classroom time, and residents who participate in this program will be optimally situated to compete for mentored career awards (K awards) at the completion of the 2 year training experience bridging residency and fellowship. Dr. Elkind, the Project Director, has independent NIH funding, as well as experience mentoring and reviewing grants, and the faculty of the program are all experienced basic, clinical, or translational researchers. The program will be evaluated primarily by the trainees' success in obtaining K08 and K23 awards, as well as by academic career placement and productivity in publications. PUBLIC HEALTH RELEVANCE: Neurological disorders, including stroke, dementia, epilepsy, and neurodegenerative conditions, are common and cause a significant burden of morbidity and mortality. Laboratory and clinical neuroscience have advanced markedly in recent years, and there is now a growing role for physician-scientists to translate developments in neuroscience into improvement in clinical care. Training young neurologists at a formative stage of their careers in research methods, and encouraging them to consider research as a career, will increase the number of committed, successful physician-scientists. This Research Education Program will provide talented neurology residents with the opportunity to develop research skills that have a high likelihood of reducing the burden of neurological disease.