Mechanisms of Mutant Epidermal Growth Factor Receptor Induced Lung Tumorigenesis
Mechanisms of Mutant Epidermal Growth Factor Receptor Induced Lung Tumorigenesis
批准号:
8099855
负责人:
KATERINA Abigail POLITI
金额:
$24.9万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2008
资助国家:
美国
项目状态:
已结题
起止时间:
2008-09-01 至 2013-06-30
关键词:
AddressAffectAllelesArginineAwardBehaviorCancer BiologyCancer ModelCellsClinicalDataDevelopmentDoxycyclineERBB2 geneEpidermal Growth Factor ReceptorEpithelial CellsEpitheliumErlotinibExonsFamilyFamily memberGefitinibGene DosageGene ExpressionGene Expression AlterationGenesGeneticGenomicsGoalsHumanKnowledgeLeadLesionLeucineLungLung AdenocarcinomaLung NeoplasmsMaintenanceMalignant NeoplasmsMalignant neoplasm of lungMediatingMemorial Sloan-Kettering Cancer CenterMentorsMusMutationNon-Small-Cell Lung CarcinomaOncogenicPatientsPharmaceutical PreparationsPhenotypePhosphotransferasesPoint MutationPositioning AttributeProgram DevelopmentRelapseRelative (related person)ResearchResearch ProposalsResistanceResourcesRoleSamplingScientistSpecimenTertiary Protein StructureTestingTetracyclinesTrainingTraining ProgramsTransgenic MiceTransgenic OrganismsTumor Suppressor GenesTyrosine Kinase DomainTyrosine Kinase InhibitorWithdrawalalveolar type II cellbasecareercareer developmentclinical phenotypegenetic analysislung carcinogenesislung tumorigenesismembermouse modelmutantnoveloverexpressionprogramsresponseskillstime usetransgene expressiontumortumor initiationtumorigenesis
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