LOS ANGELES BASIN CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE

洛杉矶盆地临床与转化科学研究所

• 批准号: 8365144
• 负责人: Thomas A Buchanan
• 金额: $ 662.28万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8365144
• 关键词: Clinical Sciences; Institutes; Los Angeles; Translational Research

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. This revised application for a Clinical and Translational Science Award (CTSA) would support the continued development ofthe Los Angeles Basin Clinical and Translational Science Institute (CTSI). Our vision is to improve health ofthe diverse and underserved population of urban Los Angeles and, in doing so, to gain knowledge that we can share with others to improve health in urban settings and megacities across the globe. In pursuit of that vision, we have established a unique partnership of leading academic, clinical and community health organizations in the urban heart of Los Angeles. We are transforming this partnership into a preeminent clinical and translational science institute focused on better heath for diverse, urban communities. We have established four main goals for the CTSI: abuild on many independent strengths to create an integrated academic home that places high priority on clinical and translational science; acreate new translational research teams and conduct projects that leverage our unique populations and partnerships to address the best scientific opportunities and most important health priorities of our local communities; Btransform education and training to create a cadre of people with a major career focus on clinical and translational research; and aimplement and disseminate what we learn to improve health in our local communities and advance translational research through regional and national networks and collaborations. To achieve these goals, we have assembled an exceptional leadership team that is creating through the CTSI: aoutstanding resources for active development of new research projects and teams, aa robust infrastructure to promote and support basic, clinical and community research, acutting edge methodologies for data acquisition, integration, management and analysis; aintegrated training of basic, clinical and community researchers using distance education and a focus on research for the diverse communities; aa novel approach to dissemination of our findings using professional communications expertise; and aa professional evaluation group to track and evaluate our progress and impact. Using $3.3M of institutional support, we have already made significant progress in transforming our local environment to a home that highly values clinical and translational research. We demonstrate strong ability to generate and support exciting new research, from the bench to our communities. With a CTSA and a pledge of $18.7M of institutional support over five vears, we will expand to a fully functional institute that will have a have a major impact to improve urban health and advance the discipline of clinical and translational research.

该子项目是对CTSA供资的百分比的估计， 用于广泛的研究领域（艾滋病研究，儿科研究，或 临床试验）。 列出的总成本仅为CTSA金额的估算 基础设施走向这一领域的研究，而不是直接提供资金， 向子项目或子项目工作人员提供NCRR补助金。 临床和转化科学奖（CTSA）的修订申请将支持洛杉矶盆地临床和转化科学研究所（CTSI）的持续发展。我们的愿景是改善洛杉矶城市多样化和服务不足人口的健康状况，并在此过程中获得我们可以与他人分享的知识，以改善地球仪城市环境和特大城市的健康状况。为了实现这一愿景，我们在洛杉矶的城市中心建立了领先的学术，临床和社区卫生组织的独特合作伙伴关系。我们正在将这种合作关系转变为一个卓越的临床和转化科学研究所，专注于为多样化的城市社区提供更好的健康。我们为CTSI建立了四个主要目标：建立许多独立的优势，以创建一个高度重视临床和转化科学的综合学术之家;建立新的转化研究团队，并利用我们独特的人口和合作伙伴关系开展项目，以解决当地社区的最佳科学机会和最重要的健康优先事项;转变教育和培训，以创造一个主要的职业生涯集中在临床和转化研究的人的骨干;并实施和传播我们所学到的，以改善我们当地社区的健康，并通过区域和国家网络和合作推进转化研究。为了实现这些目标，我们组建了一个卓越的领导团队，通过CTSI创建：积极发展新研究项目和团队的优秀资源，促进和支持基础，临床和社区研究的强大基础设施，为数据采集，整合，管理和分析提供尖端方法; a利用远程教育对基础、临床和社区研究人员进行综合培训，并侧重于为不同社区开展研究; a利用专业通信专门知识传播我们的研究结果的新方法;以及一个专业的评估小组来跟踪和评估我们的进展和影响。利用330万美元的机构支持，我们已经在将当地环境转变为高度重视临床和转化研究的家园方面取得了重大进展。我们展示了强大的能力，以产生和支持令人兴奋的新研究，从板凳到我们的社区。通过CTSA和五年内1870万美元的机构支持承诺，我们将扩大到一个功能齐全的研究所，这将对改善城市健康和推进临床和转化研究学科产生重大影响。