2009 Glycobiology Gordon Research Conference

描述(申请人提供)：这是一份为期多年的申请，申请部分资助将于2009年1月和2011年在加利福尼亚州文图拉的文图拉海滩万豪酒店举行的两年一次的戈登糖生物学研究会议。上一次会议于2007年3月在文图拉举行，并获得了全部认购。糖生物学戈登会议是介绍糖生物学领域最新和最重要研究的最负盛名的论坛之一。2009年和2011年的会议将延续强调所有类型的大分子糖共轭的结构、功能和生物学的传统。下文简要介绍了2009年会议的计划，并作为2011年会议的模板。上午和晚上安排了11次口头会议。讲座将涵盖以下主题：结构糖生物学(酶和蛋白质)、糖基化机制、神经和肌肉糖生物学、结构糖生物学(糖和糖组分)、免疫细胞糖生物学、血管糖生物学、发育糖生物学、癌症与细胞调节、代谢调节、微生物糖生物学。招贴会将在四个全天的下午晚些时候举行，并将在晚间会议后继续非正式地进行。有几个因素促成了这次会议在糖生物学领域的独特成功：a)每次口头陈述(包括简短演讲)结束时都有5分钟的讨论窗口，b)会议是在一个与世隔绝的环境中举行的，所有与会者在会外一起用餐和社交，c)计划在下午开展社交活动以促进联网，以及d)海报展示全天可用，并为晚间会议后的茶点提供背景，这确保了最大限度的曝光。演讲者和参与者将被挑选出来，以反映糖生物学领域的国际卓越水平，并确保适当的平衡，确保年轻科学家、女性和少数群体的代表性。除了约31个受邀演讲外，还将从优秀的海报摘要中挑选26个简短的口头演讲，以带来该领域的最新发展，并将为研究生、博士后和非常初级的教师提交的优秀摘要提供8个会议奖(会议费延期)。在这个高度多学科的领域中，主题的广度和所采用的技术的多样性将吸引对糖共轭化合物及其功能有共同兴趣的不同的科学家群体。所有申请者将被鼓励提交一张海报。今年会议的规模已扩大到150人。有适当的设施来容纳残疾人，他们在挑选与会者和演讲者时也将得到平等的考虑。会议将汇集该领域的领先和发展中的科学家，介绍和评估该领域的最新和最热门的研究，旨在促进糖生物学中新兴技术和概念在所有生物医学研究领域的前沿领域的广泛应用。 与公共健康相关：蛋白质和脂类的糖基化在许多重要方面有助于发育和生理上所有组织和器官的正常功能和健康。“糖生物学”领域最近经历了一次高潮，原因是新技术及其成功地促进了对人类一系列遗传、后天和传染病的机械性理解。总体而言，糖依赖疾病通过生物合成、分析方法和对表型和疾病症状的解释的共同逻辑而团结在一起，而糖生物学戈登会议提供了一个独特的论坛，将来自不同学科的研究人员聚集在一起，深入探讨这些问题。

DESCRIPTION (provided by applicant): This is a multi-year application for partial support of the biennial Gordon Research Conference on Glycobiology to be held in January 2009 and 2011 at the Ventura Beach Marriott in Ventura, CA. The previous conference was held March 2007 in Ventura, and was fully subscribed. The Glycobiology Gordon Conference is one of the most prestigious forums for the presentation of the latest and most significant research in the area of Glycobiology. The 2009 and 2011 conferences will continue a tradition of emphasis on the structure, function, and biology of macromolecular glycoconjugates of all types. Plans for the 2009 conference are described briefly below and serve as a template for the 2011 meeting. Eleven oral sessions are scheduled for mornings and evenings. The lecture sessions will cover the following topics: Structural Glycobiology (enzymes & Proteins), Mechanisms of Glycosylation, Nerve and Muscle Glycobiology, Structural Glycobiology (glycans & glycomics), Immune Cell Glycobiology, Vascular Glycobiology, Developmental Glycobiology, Cancer & Cell Regulation, Metabolic Regulation, Microbial Glycobiology. Poster sessions will be held each of the four full days in the late afternoon, and will continue informally after the evening sessions. Several factors contribute to the unique success of this conference in the Glycobiology community: a) a 5-minute window of discussion is enforced at the end of each oral presentation (including short talks), b) the conference is held in a cloistered setting where all participants dine and socialize together outside of the sessions, c) afternoon social activities are planned to promote networking, and d) the poster displays are accessible throughout the day and provide the backdrop for refreshments after the evening sessions, which ensures maximal exposure. Speakers and participants will be selected to reflect the international excellence in glycobiology with appropriate balance ensuring representation of young scientists, women, and minorities. In addition to the approximately 31 invited talks, 26 short oral presentations will be selected from outstanding poster abstracts to bring forth the latest developments in the field, and eight Conference Awards (conference fee deferrals) will be available for outstanding abstracts submitted by graduate students, post-docs, and very junior faculty. The breadth of topics and the diversity of techniques employed in this highly multidisciplinary field will attract a diverse group of scientists with a common interest in glycoconjugates and their functions. All applicants will be encouraged to present a poster. The size of the conference has been increased this year to 150 participants. Proper facilities are available to accommodate handicapped individuals who will also be considered equally in the selection of attendees and speakers. The meeting will bring together the leading and developing scientists in the field to present and evaluate the latest and hottest research in the area, and is designed to stimulate the widening application of emerging technologies and concepts in glycobiology to the frontiers of all areas of biomedical research. PUBLIC HEALTH RELEVANCE: Glycosylation of proteins and lipids contributes in many essential ways to the normal function and health of all the tissues and organs in both development and physiology. The field of `Glycobiology' has experienced a recent upsurge on account of new technologies and its success in contributing a mechanistic understanding to a wide range of inherited, acquired and infectious diseases in humans. Collectively, glycan-dependent diseases are united by a common logic of biosynthesis, analytical methodologies and interpretation of phenotypes and disease symptoms, and the Glycobiology Gordon Conference offers a unique forum to bring together investigators from diverse disciplines to intensively explore these issues.