A Self-Assessment Intervention for Young Adult Polydrug Users at Risk for HIV

针对有艾滋病毒风险的年轻成年多吸毒者的自我评估干预措施

• 批准号: 8073629
• 负责人: Steven P Kurtz
• 金额: $ 56.13万
• 依托单位: NOVA SOUTHEASTERN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-08-01 至 2015-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8073629
• 关键词: Age; Aging; Alcohol or Other Drugs use; Behavior; Behavioral; Cocaine; Dancing; Data; Drug usage; Drug user; Effectiveness; Environmental Risk Factor; Equipment and supply inventories; Evaluation Research; Florida; Freedom; HIV; HIV Infections; Health; Health Status; Heterosexuals; Internet; Intervention; Interviewer; Knowledge; Literature; Measures; Mental Health; Natural History; Outcome; Outcome Measure; Parents; Participant; Pharmaceutical Preparations; Play; Population; Prevalence; Process; Public Health; Qualitative Research; Randomized Clinical Trials; Recording of previous events; Relative (related person); Reporting; Resistance; Risk; Risk Assessment; Risk Behaviors; Risk Reduction; Risk Reduction Behavior; Sampling; Self Administration; Self Assessment; Self Perception; Self-Administered; Sex Behavior; Sexual Partners; Social Problems; Substance abuse problem; Theoretical model; Time; Unsafe Sex; Vulnerable Populations; Woman; alcohol and other drug; arm; authority; base; behavior change; brief intervention; club drug; cost; demographics; design; ecstasy; efficacy testing; follow-up; high risk; high risk sexual behavior; instrument; intervention effect; men; novel; parent grant; peer; programs; public health relevance; response; sex risk; social; young adult

DESCRIPTION (provided by applicant): Drug use is normative in urban club scenes, with MDMA (ecstasy) and cocaine being the most prevalent "club" drugs. The parent grant which this application proposes to continue has documented not only high rates of mental health problems and extensive arrest and abuse histories, but also unexpectedly and alarmingly high rates of undiagnosed HIV infection among a predominately heterosexual young adult sample. The parent grant, now in its fifth year, is an 18-month longitudinal natural history study of 600 club and prescription drug using young adults. A key finding from that study is the extent to which the comprehensive health and social risk assessments induced participants to reduce their substance use and sexual risk behaviors. Over 70% of participants substantially reduced their substance use at the first follow-up assessment after baseline. Qualitative research with study completers showed that participants attributed the strong intervention effect of the baseline assessment to: 1) the friendly, non-judgmental field staff of age-peers; 2) the thorough and detailed assessments; and 3) an emerging self-awareness of substance use-related problems based on their responses to the assessment items. Study completers also reported that risk reduction tended to occur precisely because the study was not framed as an intervention. Within this context, the specific aims of the proposed 5-year renewal project are to: 1) identify the covariates of baseline substance abuse and sexual risks (including demographics, social risk measures, peer norms, abuse history, and mental health status) among a sample of 750 heterosexually active, not-in-treatment, club and prescription drug users ages 18 to 39 in Miami, Florida; 2) evaluate, through random assignment, the relative effectiveness of two intervention conditions and a waitlist control in reducing sex risks and drug use, as measured at 3-, 6- and 12-month follow-ups: Arm 1, an interviewer-administered comprehensive health and social risk assessment intervention (CAPI Intervention) similar to the baseline instrument used in the parent grant; Arm 2, an identical self-administered comprehensive assessment intervention (ACASI Intervention); and Arm 3, a waitlist control condition (Control). Outcome measures, including past 90-day counts of unprotected sex acts and days' drug use, will be obtained from brief risk behavior inventories at baseline and follow-ups; and 3) conduct qualitative process evaluation research with 40 participants in each study arm to contextualize the study findings and intervention outcomes. The proposed project is significant, as it responds to the need for brief interventions for a highly vulnerable, high risk population. The self-assessment intervention, if proven efficacious in reducing HIV risk, could be delivered at low cost and broad scale, and might well be adaptable to other high risk groups who are resistant to public health warnings and/or professional intervention. PUBLIC HEALTH RELEVANCE: Club drug users report high levels of sexual risk behaviors as well as other problems related to substance use. The proposed study is a randomized clinical trial to evaluate the efficacy of a substance use and sexual risk reduction intervention among heterosexually active men and women in the club culture. The self-assessment intervention, if proven efficacious in reducing HIV risk, could be delivered at low cost and broad scale, and might well be adaptable to other high risk groups who are resistant to public health warnings and/or professional intervention.

描述（由申请人提供）：在城市俱乐部场景中，药物使用是规范的，MDMA（摇头丸）和可卡因是最流行的“俱乐部”药物。这项申请建议继续提供的父母补助金不仅记录了高比例的精神健康问题和广泛的逮捕和虐待历史，而且在以异性恋为主的年轻成年人样本中，未确诊的艾滋病毒感染率也出乎意料地高得惊人。 父母补助金，现在在其第五个年头，是一个为期18个月的纵向自然史研究600俱乐部和处方药使用的年轻人。该研究的一个关键发现是综合健康和社会风险评估在多大程度上促使参与者减少药物使用和性风险行为。超过70%的参与者在基线后的第一次随访评估中大幅减少了他们的物质使用。与研究完成者的定性研究表明，参与者将基线评估的强烈干预效果归因于：1）年龄同龄人的友好，非评判性的现场工作人员; 2）全面和详细的评估;和3）基于他们对评估项目的反应，对药物使用相关问题的自我意识正在形成。研究完成者还报告说，风险降低往往恰恰是因为研究不是作为一种干预措施。 在此背景下，拟议的5年更新项目的具体目标是：1）确定基线药物滥用和性风险的协变量（包括人口统计学，社会风险措施，同伴规范，滥用历史，和心理健康状况）的样本中的750名异性恋活跃，非治疗，俱乐部和处方药使用者，年龄在迈阿密，佛罗里达; 2）通过随机分配，评估两种干预条件和一个等待名单控制在减少性风险和药物使用方面的相对有效性，在3个月、6个月和12个月的随访中进行测量：第1组，一个由访谈者管理的综合健康和社会风险评估干预。（CAPI干预），类似于父母补助中使用的基线工具;组2，相同的自我管理的综合评估干预（ACASI干预）;组3，候补控制条件（对照）。结果测量，包括过去90天无保护性行为计数和药物使用天数，将在基线和随访时从简要的风险行为清单中获得; 3）每个研究组中有40名参与者进行定性过程评估研究，以将研究结果和干预结果置于背景中。 拟议的项目意义重大，因为它满足了对高度脆弱、高风险人群进行短暂干预的需要。自我评估干预措施如果被证明在降低艾滋病毒风险方面有效，则可以低成本和大规模地提供，并且很可能适用于对公共卫生警告和/或专业干预措施有抵抗力的其他高危人群。 公共卫生相关性：俱乐部吸毒者报告高水平的性风险行为以及其他与药物使用有关的问题。这项研究是一项随机临床试验，旨在评估俱乐部文化中异性恋活跃男性和女性的物质使用和性风险降低干预的有效性。自我评估干预措施如果被证明在降低艾滋病毒风险方面有效，则可以低成本和大规模地提供，并且很可能适用于对公共卫生警告和/或专业干预措施有抵抗力的其他高危人群。