Combination Clostridium Difficile Toxin and Adhesin Vaccine

艰难梭菌毒素和粘附素联合疫苗

• 批准号: 8337121
• 负责人: DAVID D HO
• 金额: $ 74.15万
• 依托单位: AARON DIAMOND AIDS RESEARCH CENTER
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-30 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8337121
• 关键词: Active Immunization; Address; Adherence; Adhesions; Adjuvant; Age; Aging; Animal Model; Antibiotics; Antibodies; Antibody Formation; Antigens; Bacillus (bacterium); Bacteria; Bacterial Adhesins; Bacterial Infections; Binding; Boston; Chimeric Proteins; Clinical; Clinical Data; Clostridium difficile; Colitis; Combined Vaccines; Communicable Diseases; Comorbidity; Development; Diarrhea; Disease; Disease Progression; Elderly; Enteral; Environmental Pollution; Epithelial Cells; Europe; Evaluation; Exhibits; Family; Flagella; Flagellin; Hamsters; Hand; Heating; Hospitalization; Hospitals; Human; Hygiene; Immune response; Immunity; Immunization; Immunoglobulin G; In Vitro; Incidence; Individual; Infection; Infection prevention; Injury; Intestines; Laboratories; Ligands; Measures; Mediating; Mesocricetus auratus; Modeling; Mus; New York; Organism; Outcome; Passive Immunization; Patient Isolation; Patients; Pattern recognition receptor; Play; Population; Prevention; Preventive; Production; Proteins; Receptor Signaling; Recombinant Fusion Proteins; Recombinants; Recurrence; Recurrent disease; Regimen; Reporting; Reproduction spores; Risk; Role; Route; Sampling; Serum; Surface; Symptoms; Testing; Toll-Like Receptor 5; Toll-like receptors; Toxin; United States; Vaccinated; Vaccination; Vaccines; Virulence Factors; Virus; adaptive immunity; base; design; design and construction; enterotoxin LT; experience; fliC gene product; fungus; immunogenic; immunogenicity; in vivo; mortality; neutralizing antibody; novel; pathogen; preclinical study; prevent; protective efficacy; receptor binding; response; success; therapeutic vaccine; vaccine candidate; vaccine efficacy