Analysis of diabetogenic human T cell receptors

致糖尿病的人类 T 细胞受体分析

• 批准号: 8311935
• 负责人: HOWARD W DAVIDSON
• 金额: $ 36.93万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-08-15 至 2013-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8311935
• 关键词: Adopted; Age; Alleles; Antigens; Appearance; Attention; Autoantibodies; Autoantigens; Autoimmune Diseases; Autoimmune Process; Autoimmunity; Beta Cell; Binding; Biological Markers; CD4 Positive T Lymphocytes; Child; Chronic Disease; Clinic; Clinical; Clinical Trials; Complex; Development; Diabetes Mellitus; Disease; Disease Progression; Drug Design; Elderly; Epitope Mapping; Epitopes; Future; Glycoproteins; Goals; Gold; Human; Humoral Immunities; Immune system; Immunodominant Epitopes; Immunosuppression; Immunosuppressive Agents; Individual; Inflammatory; Insulin; Insulin-Dependent Diabetes Mellitus; Investigation; Knowledge; Libraries; Ligands; MHC Class II Genes; Maps; Mediating; Metabolic; Molecular; Molecular Analysis; Molecular Target; Monitor; Natural History; Patients; Peptides; Persons; Phenotype; Population; Predisposition; Process; Proinsulin; Property; Proteins; Proteomics; Protocols documentation; Reagent; Relative (related person); Research; Role; Series; Specificity; Structure of beta Cell of islet; T cell response; T-Cell Receptor; T-Lymphocyte; T-Lymphocyte Epitopes; Testing; Therapeutic; Therapeutic Agents; Therapeutic Intervention; Thymoma; Tissues; Translating; Work; autoreactive T cell; autoreactivity; base; chemokine; cytokine; diabetic; diabetic patient; economic impact; high risk; insight; islet; man; member; next generation; novel therapeutics; peripheral blood; prevent; reconstitution; research study; retroviral-mediated; socioeconomics; therapeutic target; young adult; zinc-binding protein