Are IL-18 receptor-bearing CD8 T cells pathogenic in human Type 1 diabetes?
Are IL-18 receptor-bearing CD8 T cells pathogenic in human Type 1 diabetes?
批准号:
8313163
负责人:
Nora E Sarvetnick
金额:
$37.13万
依托单位国家:
美国
项目类别:
财政年份:
2011
资助国家:
美国
项目状态:
已结题
起止时间:
2011-08-15 至 2013-07-31
关键词:
Animal ModelAntigensAutoimmune DiseasesAutoimmunityBinding ProteinsBiological AssayBlood specimenCD8 receptorCD8B1 geneCandidate Disease GeneCeliac DiseaseCellsClinical TrialsDataDevelopmentDiabetes MellitusDiseaseDisease susceptibilityEnvironmentEvaluationExperimental ModelsFlow CytometryFrequenciesGenerationsGenomicsGoalsGrowthHealthHome environmentHumanImmuneIn VitroIndividualInsulin-Dependent Diabetes MellitusInterleukin-18Islet CellIslets of LangerhansLicensingLinkMemoryMusPancreasPathogenesisPathway interactionsPatientsPhenotypePopulationPreventionProcessPropertyProteinsQuality of lifeReceptor CellReportingResearchRheumatoid ArthritisRisk FactorsRoleSignal TransductionStagingStimulusSurrogate MarkersT-Cell ReceptorT-LymphocyteTestingTherapeutic InterventionTissue SampleWorkbasecytotoxicdiabeticexpectationinsightisletreceptorresponse
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会议论文
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国内基金
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