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Synapt ion mobility mass spectrometer

Synapt ion mobility mass spectrometer
突触离子淌度质谱仪
批准号：
7842443
负责人：
PIETER C DORRESTEIN
金额：
$80.24万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN DIEGO
依托单位国家：
美国
项目类别：
财政年份：
2011
资助国家：
美国
项目状态：
已结题
起止时间：
2011-06-15 至 2012-06-14
来源：
https://reporter.nih.gov/project-details/7842443
关键词：
Cell CommunicationCell physiologyCellsDoctor of PharmacyDoctor of PhilosophyEquipmentFuture GenerationsStudentsTherapeuticTherapeutic EffectTrainingdrug developmentinstrumention mobilitymass spectrometernovel therapeuticstherapeutic target

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中文摘要
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英文摘要
DESCRIPTION (provided by applicant): This proposal is for a Synapt ion mobility mass spectrometer and will be used for the characterization of therapeutics. The instrument is also used to characterize the effect of therapeutics on cellular processes and cell-to cell communication. This equipment will be used to train the future generation of Doctors of Pharmacy and PhD students engaged in drug development. Finally, the Synapt ion mobility mass spectrometer enables the discovery of the next generation therapeutics and therapeutic targets. PUBLIC HEALTH RELEVANCE: This proposal is requesting funds for a mass spectrometry instrument that is to be used to uncover targets of disease and the discovery and characterization of novel therapeutics.
期刊论文(5)
专著(0)
科研奖励(0)
会议论文
Leucanicidin and Endophenasides Result from Methyl-Rhamnosylation by the Same Tailoring Enzymes in Kitasatospora sp. MBT66.
DOI： 10.1021/acschembio.5b00801
发表时间： 2016-02
期刊： ACS chemical biology
影响因子： 4
作者： [Changsheng Wu;M. Medema;Rianne Läkamp;Le Zhang;P. Dorrestein;Y. Choi;G. V. van Wezel]
通讯作者： Changsheng Wu;M. Medema;Rianne Läkamp;Le Zhang;P. Dorrestein;Y. Choi;G. V. van Wezel
Evolution of metabolic divergence in Pseudomonas aeruginosa during long-term infection facilitates a proto-cooperative interspecies interaction.
DOI： 10.1038/ismej.2015.220
发表时间： 2016-06
期刊： The ISME journal
影响因子： --
作者： []
通讯作者：
Reverse Metabolomics for the Discovery of Disease Associated Microbial Molecules
Collaborative Microbial Metabolite Center
Cross Repository Metabolomics Data and Workflow Integration
Mapping the Secondary Metabolomes of Marine Cyanobacteria
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