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PRODUCT DEVELOPMENT OF A MEMBRANE TETRASPANIN VACCINE AGAINST SCHISTOSOMIASIS

PRODUCT DEVELOPMENT OF A MEMBRANE TETRASPANIN VACCINE AGAINST SCHISTOSOMIASIS
血吸虫病膜四跨膜疫苗的产品开发
批准号：
8186912
负责人：
Jeffrey Michael Bethony
金额：
$56.18万
依托单位：
ALBERT B. SABIN VACCINE INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
2011
资助国家：
美国
项目状态：
已结题
起止时间：
2011-01-01 至 2013-09-30
来源：
https://reporter.nih.gov/project-details/8186912
关键词：
AdjuvantAffectAfricaAftercareAlhydrogelAnimalsAntibodiesAntigensAreaBindingBiochemicalBrazilCaribbean regionCessation of lifeCharacteristicsChronicCircular DichroismClinicClinicalContractorCountryDNA VaccinesDataDeveloping CountriesDevelopmentDiseaseDistrict of ColumbiaDoseDrug FormulationsDrug resistanceEnsureExcipientsFamilyFermentationFluorescenceFoundationsFundingGenerationsGoalsHeadHumanImmunityImmunology procedureIndividualInfectionInstitutesInternationalIntestinal SchistosomiasesInvestigational New Drug ApplicationItalyLaboratory AnimalsLeadLifeLinkLow incomeMalariaManufacturer NameMarylandMeasuresMembraneMethodologyMolecularMorbidity - disease rateNatureNorth CarolinaOral Poliovirus VaccineOutcomeParasitesParasitic infectionPharmaceutical PreparationsPichiaPraziquantelPreclinical TestingPrincipal InvestigatorProcessProgram DevelopmentProgram ReviewsProteinsProteomicsPublic SectorPublishingQuality ControlRecombinant ProteinsRecombinant VaccinesRecombinantsReproducibilityResearch ContractsResistanceRiskRisk ManagementSchistosomaSchistosoma mansoniSchistosomiasisSerumStagingSurfaceSurface AntigensTechnologyTechnology TransferTestingThrombospondin 1TimeToxicologyTropical DiseaseTuberculosisTuberculosis VaccinesUnited StatesUnited States Food and Drug AdministrationUnited States National Institutes of HealthVaccine ResearchVaccinesWhole OrganismWorkYeastsaluminum phosphatealuminum sulfateassay developmentauthoritybaseburden of illnesschemotherapycombatcostdisabilityefficacy testingexperienceexpression vectorextracellularfrontierhuman PHEMX proteinhuman subjectinnovationinnovative technologieslight scatteringmanufacturing processmeetingsneglectnovelnovel strategiespotency testingpreventproduct developmentprogramspublic-private partnershipresearch clinical testingresponsescale upstability testingsuccessthrombospondin 2thrombospondin 3toolvaccine candidatevaccine developmentvaccine evaluation

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